Combined oral contraceptives (COC) is one of the most widely used contraceptive method in the world. However, the occurrence of drug interactions can affect ...
Karolina
1 Kilinska ,
Magdalena
2 Cerbin-Koczorowska ,
Michal
3 Michalak ,
Arleta
2 Matschay
1Student’s
Scientific Club of Pharmaceutical Care,Department of Pharmaceutical Technology, Pharmacy Practice Division, Poznan University of Medical Sciences, 70 Bukowska Street, 60-812 Poznan, Poland 2Department of Pharmaceutical Technology, Pharmacy Practice Division, Poznan University of Medical Sciences, 70 Bukowska Street, 60-812 Poznan, Poland 3 Department of Computer Science and Statistics, Poznan University of Medical Sciences, 79 Dabrowskiego Street, 60-529 Poznan, Poland
Combined oral contraceptives (COC) is one of the most widely used contraceptive method in the world. However, the occurrence of drug interactions can affect the effectiveness and safety of COC and other drugs [1]. The aim of the study was to detect potential drug-drug interactions of COCs among Polish females with the use of detailed drug reviews and to assess their effectiveness.
Cross-sectional descriptive, retrospective pilot study was carried out from March 2013 to February 2014 among Polish females. Mixed methods research was chosen to gather both quantitative (patients’ sociodemographics, contraceptive behaviors) and qualitative data (products used concomitantly with COC by the patient each month). To assess the effectiveness of conducted reviews the relationship between two variables: the number of drug listed in the questionnaire and the number of potential drug-drug interactions was described with the use of Spearman's rank correlation coefficient founded as statistically significant at the level of p
