In article number 1701527, Sangeeta N. Bhatia and co-workers engineer an antibacterial by fusing two peptide domains to target and kill bacteria and thenĀ ...
In article number 1701527, Sangeeta N. Bhatia and co-workers engineer an antibacterial by fusing two peptide domains to target and kill bacteria and then encapsulate them in a biodegradable porous silicon nanoparticle. These nanomaterials kill bacteria and improve animal survival after treatment of a lung-infection model. This approach represents a new strategy for the development of antibacterials to combat the rising incidence of antibiotic resistance in the clinic.