Jun 8, 2018 - Olivier Le Polain De Warouxa, W. John Edmundsa, Kensuke Takahashi b, Koya Ariyoshib ..... hq/2009/WHO_FCH_CAH_NCH_09.04_eng.pdf].
Human Vaccines & Immunotherapeutics
ISSN: 2164-5515 (Print) 2164-554X (Online) Journal homepage: http://www.tandfonline.com/loi/khvi20
Predicting the impact of pneumococcal conjugate vaccine programme options in Vietnam Olivier Le Polain De Waroux, W. John Edmunds, Kensuke Takahashi, Koya Ariyoshi, E. Kim Mulholland, David Goldblatt, Yoon Hong Choi, Dang Duc Anh, Lay Myint Yoshida & Stefan Flasche To cite this article: Olivier Le Polain De Waroux, W. John Edmunds, Kensuke Takahashi, Koya Ariyoshi, E. Kim Mulholland, David Goldblatt, Yoon Hong Choi, Dang Duc Anh, Lay Myint Yoshida & Stefan Flasche (2018): Predicting the impact of pneumococcal conjugate vaccine programme options in Vietnam, Human Vaccines & Immunotherapeutics, DOI: 10.1080/21645515.2018.1467201 To link to this article: https://doi.org/10.1080/21645515.2018.1467201
© 2018 The Author(s). Published with license by Taylor & Francis
View supplementary material
Accepted author version posted online: 21 May 2018. Published online: 08 Jun 2018.
Submit your article to this journal
Article views: 93
View related articles
View Crossmark data
Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=khvi20
HUMAN VACCINES & IMMUNOTHERAPEUTICS 2018, VOL. 0, NO. 0, 1–9 https://doi.org/10.1080/21645515.2018.1467201
RESEARCH PAPER
Predicting the impact of pneumococcal conjugate vaccine programme options in Vietnam Olivier Le Polain De Warouxa, W. John Edmundsa, Kensuke Takahashi b, Koya Ariyoshib, E. Kim Mulhollanda,c, David Goldblattd, Yoon Hong Choie,f, Dang Duc Anhg, Lay Myint Yoshidab, and Stefan Flaschea a Centre for the mathematical modelling of infectious diseases, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK; bInstitute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; cMenzies School of Health Research, Charles Darwin University, Darwin, Australia; dInstitute of Child Health, University College London, London, UK; eImmunisation, Hepatitis and Blood Safety Department, Public Health England, London, UK; fModelling and Economics Unit, Public Health England, London, UK; gNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam
ABSTRACT
ARTICLE HISTORY
Although catch-up campaigns (CCs) at the introduction of pneumococcal conjugate vaccines (PCVs) may accelerate their impact, supply constraints may limit their benefit if the need for additional PCV doses results in introduction delay. We studied the impact of PCV13 introduction with and without CC in Nha Trang, Vietnam – a country that has not yet introduced PCV – through a dynamic transmission model. We modelled the impact on carriage and invasive pneumococcal disease (IPD) of routine vaccination (RV) only and that of RV with CCs targeting
