R-128. Identification of laboratory factors contributing to a 50 ...

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Mayer J., Nechiri F., Weedon V., Jones E., Kalin H.,. Oehninger S., Toner J., Gibbons W. and Muasher S. The Jones Institute for Reproductive Medicine, Eastern.
Abstracts of the 15th Annual Meeting of the ESHRE, Tours, France 1999

procedure (embryos eligible for transfer contained 38 years of age or who had two or more unsuccessful treatment cycles previously.

Results: The mean age of the woman and the mean number of MIl oocytes injected were not different significantly between the two groups. When parameters were analysed individually, a higher normal fertilization rate and a higher proportion of good quality embryos were detected in group 2 that were related to the modified microinjection technique and to the modified culture method respectively. Pregnancy and implantation rates were significantly higher in group 2 when parameters were analysed collectively (Table I). Table I. Group 1 Total no. of initiated cycles 174 Age of women" 32.2 ± 4.6 MIl oocytes injected" 9.6 ± 4.4 65.8 ± 18.6 2PN oocytes (%)a 67.2 ± 17.9 Transferable quality embryos (% )a* Embryos transferred/cycle'< 3.4 ± 1.2 Cycles with embryo transfer (% of total) 165 (94.8) 64 (38.7) Pregnancy/cycle with ET (%)* Embryo implanted/embryo transferred (%)* 90/557 (16.1)

Group 2 228 33.4 ± 4.8 10.3 ± 5.9 70.0 ± 20.8 84.1 ± 19.7 3.1 ± 1.0 216 (94.7) 107 (49.5) 136/681 (20.0)

"Mean ± SD.