Relationship between fine particulate air pollution and ... - Heart - BMJ

6 downloads 0 Views 784KB Size Report
Oct 23, 2014 - air pollution has become a serious issue in China.2. From 21 February 2014 to 26 February 2014, heavy smog lingered over Beijing, and the ...
Cardiac risk factors and prevention

ORIGINAL ARTICLE

Relationship between fine particulate air pollution and ischaemic heart disease morbidity and mortality Wuxiang Xie,1 Gang Li,2 Dong Zhao,1 Xueqin Xie,3 Zaihua Wei,2 Wei Wang,1 Miao Wang,1 Guoxing Li,4 Wanru Liu,3 Jiayi Sun,1 Zhangrong Jia,1 Qian Zhang,1 Jing Liu1 ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ heartjnl-2014-306165). 1

Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China 2 Information Statistics Center, Beijing Center for Diseases Prevention and Control, Beijing, China 3 Beijing Public Health Information Center, Beijing, China 4 Department of Occupational and Environmental Health, School of Public Health, Peking University, Beijing, China Correspondence to Professor Jing Liu, Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, No. 2 Anzhen Street, Chaoyang District, Beijing, China; [email protected] Received 6 May 2014 Revised 16 September 2014 Accepted 3 October 2014 Published Online First 23 October 2014

ABSTRACT Objective To assess the relationship between fine particulate matter (PM2.5) concentration and ischaemic heart disease (IHD) morbidity and mortality. Methods A time-series study conducted in Beijing from 1 January 2010 to 31 December 2012. Data on 369 469 IHD cases and 53 247 IHD deaths were collected by the Beijing Monitoring System for Cardiovascular Diseases, which covers all hospital admissions and deaths from IHD from Beijing’s population of 19.61 million. Results The mean daily PM2.5 concentration was 96.2 μg/m3 with a range from 3.9 to 493.9 μg/m3. Only 15.3% of the daily PM2.5 concentrations achieved WHO Air Quality Guidelines target (25 μg/m3) in the study period. The dose–response relationships between PM2.5 and IHD morbidity and mortality were non-linear, with a steeper dose–response function at lower concentrations and a shallower response at higher concentrations. A 10 μg/m3 increase in PM2.5 was associated with a 0.27% (95% CI 0.21 to 0.33%, p5000 people/km2). The area also covers 97.8% (44/45) of the tertiary hospitals and 79.3% (69/87) of the secondary hospitals in Beijing that admit IHD cases. If the cumulative time of missing hourly PM2.5 data was