RESEARCH ARTICLE
Role of maternal preconception nutrition on offspring growth and risk of stunting across the first 1000 days in Vietnam: A prospective cohort study Melissa F. Young1*, Phuong Hong Nguyen2,3, Ines Gonzalez Casanova1, O. Yaw Addo1, Lan Mai Tran2, Son Nguyen2, Reynaldo Martorell1, Usha Ramakrishnan1
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1 Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America, 2 International Food Policy Research Institute, Washington, District of Columbia, United States of America, 3 Thai Nguyen University of Pharmacy and Medicine, Thai Nguyen, Vietnam *
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Abstract OPEN ACCESS Citation: Young MF, Nguyen PH, Gonzalez Casanova I, Addo OY, Tran LM, Nguyen S, et al. (2018) Role of maternal preconception nutrition on offspring growth and risk of stunting across the first 1000 days in Vietnam: A prospective cohort study. PLoS ONE 13(8): e0203201. https://doi.org/ 10.1371/journal.pone.0203201 Editor: Nick Ashton, The University of Manchester, UNITED KINGDOM Received: May 14, 2018 Accepted: August 10, 2018 Published: August 30, 2018 Copyright: © 2018 Young et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: Funding for this research was provided by the Thrasher Research Fund (https://www. thrasherresearch.org/default.aspx), Nestle Foundation (http://www.nestlefoundation.org/e/), Micronutrient Initiative (https://mathileinstitute.org) and the Mathile Institute for Advancement of Human Nutrition (https://mathileinstitute.org). The
Growing evidence supports the role of preconception maternal nutritional status (PMNS) on birth outcomes; however, evidence of relationships with child growth are limited. We examined associations between PMNS (height, weight and body mass index- BMI) and offspring growth during the first 1000 days. We used prospective cohort data from a randomized-controlled trial of preconception micronutrient supplementation in Vietnam, PRECONCEPT (n = 1409). Poisson regression models were used to examine associations between PMNS and risk of offspring stunting (
