Phosphatase Measurement Discriminating Prostate Carcinoma ... KEY WORDS : Total Prostate Specific Antigen, Prostatic Acid Phosphatase, Benign Prostatic ...
International Journal of Pharmaceutical Science Invention ISSN (Online): 2319 – 6718, ISSN (Print): 2319 – 670X www.ijpsi.org Volume 3 Issue 1‖ January 2014 ‖ PP.36-40
Serum Total Prostatic Specific Antigen and Prostatic Acid Phosphatase Measurement Discriminating Prostate Carcinoma from Benign Prostatic Hyperplasia in Sudanese Patients Haala M. Gabra1*; Adbelgadir A Elmugadam 2; Badereldein H Elabid 3; Ghada A.Elfadil2, Mohamed H. Arbab 4;Elmutuz H.Elssaig 5; 1,
2,
Clinical Chemistry, Laboratory department, Fedail Hospital. Clinical Chemistry, department of FMLS, Sudan University of Science and Technology. 3, Chemical Pathology, department of FMLS, University of Science and Technology. 4, Medical Microbiology, department of FMLS, Omduraman Ahlia University. 5, Clinical Chemistry, department of FMLS, Al-Zaiem Al-Azhari University.
ABSTRACT : This is a prospective, analytical, hospital based, case control study. The aim of this study was to evaluate the clinical utility of total prostate specific antigen (TPSA) and prostatic acid phosphatase (PAP) for distinction between prostate carcinoma (PCa) and Benign prostatic hyperplasia (BPH) in Sudanese patients in Khartoum state.This study was carried out in Fedail Medical Hospital during the period of 2010 to 2012. It was performed on 200 patients as the study group and 100 healthy volunteers as the control group. The age for the control group and the study group were matched. Serum level of TPSA was measured by Roche immunoassay cobas e411 and serum PAP level was measured spectrophotometericaly.The mean level of serum TPSA was (42.6±27.2) and (7.8±5.1) for PCa & BPH respectively ( p
