Short-term airborne particulate matter exposure alters ...

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Nov 13, 2014 - Additional file 1: Clustered heatmaps of the observed correlations between our full MAPK gene set and those shown to be associated with air ...
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Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogenactivated protein kinase network: a cross-sectional study Juan Jose Carmona, Tamar Sofer, John Hutchinson, Laura Cantone, Brent Coull, Arnab Maity, Pantel Vokonas, Xihong Lin, Joel Schwartz and Andrea A Baccarelli Environmental Health 2014, 13:94 doi:10.1186/1476-069X-13-94 Published: 13 November 2014 Additional file 1: Clustered heatmaps of the observed correlations between our full MAPK gene set and those shown to be associated with air pollution. (A) Unadjusted DNA methylation coefficients were used to cluster the 84 genes listed in Table 1; (B) clustering of adjusted methylation coefficients, after accounting for all relevant confounders included in this study—age, blood pressure, smoking status, blood cell proportions, etc. (described in Methods); similarly, the same is shown for the 27 MAPK gene hits from Table 3, prior to adjusting for all confounders (C) and afterwards (D). Format: ZIP Size: 2.6MB http://www.ehjournal.net/content/13/1/94/additional [Data located in subsequent pages.]

 

Carmona  et  al.,  Additional  Files,  page  1  

Additional file 1A: 10018_7989112011285506_add1A.jpeg

 

Carmona  et  al.,  Additional  Files,  page  2  

Additional file 1B: 10018_7989112011285506_add1B.jpeg

 

Carmona  et  al.,  Additional  Files,  page  3  

Additional file 1C: 10018_7989112011285506_add1C.jpeg

 

Carmona  et  al.,  Additional  Files,  page  4  

Additional file 1D: 10018_7989112011285506_add1D.jpeg

 

Carmona  et  al.,  Additional  Files,  page  5