Simultaneous Estimation of Metformin Hydrochloride and Pioglitazone ...

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Laheji RJ, Strukenboom MC, Hassing RJ, Dieleman J, Stricker BH. 4. Risk of community-acquired pneumonia and use of gastric acid- suppressive drugs.

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TABLE 2: ANTIULCER ACTIVITY DATA OF COMPOUNDS P(1-9) Compound Control Omeprazole P1 P2 P3 P4 P5 P6 P7 P8 P9

Total acid (mEq/l) 11.4± 1.6 3.2± 1.25* 8.69±0.21* 8.31±0.29* 6.4±0.75* 9.04±0.34* 7.3±0.57* 4.8±0.55* 5.02±0.35* 8.21±0.34* 6.04±0.15*

Free acid (mEq/l) 3.18±0.29 0.42±0.25* 2.52±0.42* 2.18±0. 38* 2.11±0.30* 2. 92±0.12* 2.41±0.17* 1.79±0.08* 1.77±0.23* 2.62±0.27* 2.13±0.02*

Ulcer index 4.4±0.35 0.33±0.06* 3.66±0.81* 3.36±0.65* 2.33±0.22* 3.4±0.29* 2.83±0.34* 1.41±0.14* 2.33±0.30* 3.17±0.27* 1.75±0.51*

4. 5. 6.

7.

8.

Each value represents the mean± SEM. No of animals in each group were 6. *p

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