Sorting through the Safety Data Haystack: Using Machine Learning to Identify Individual Case Safety Reports (ICSRs) in Social-Digital Media Drug Safety Shaun Comfort, Sujan Perera, Zoe Hudson, Darren Dorrell, Shawman Meireis, Meenakshi Nagarajan, Cartic Ramakrishnan and Jennifer Fine Corresponding Author: Shaun Comfort, MD Genentech - A Member of the Roche Group South San Francisco, CA 94080
[email protected] Electronic Supplementary Material 1 Table of keywords used in search for social digital media posts containing potential ICSRs. Roche Brands 454 Life Sciences Ariosa Ariosa Diagnostics Bina Technologies BioImagene Capp Medical Chugai Foundation Medicine Genentech Geneweave Glycart InterMune Kapa Biosystems NimbleGen Ventana Roche Roche Group F. Hoffmann-La Roche AG Roche Holding AG F. Hoffmann-La Roche AG NOT: Tony Roche NOT: Daniel Roche NOT Tony Roche
Roche Products Accu-Chek;;;;;454 Sequencing GS junior Accutane;;;;;accuchek Roaccutan*;;;;;Accu-Chek Accutrend;;;;;Accutane ACE910;;;;; Actemra;;;;;Accutrend Activase;;;;;Accutrend Actonel;;;;;Acid phosphatase Alecensa;;;;;Actemra Aleglitazar;;;;;ACTH AmpliChip;;;;;Activase AmpliCor;;;;;Actonel anaprox;;;;;AFB III anti-HCV Immunoassay;;;;;AFP Atezolizumab;;;;;Alcian Blue Avastin;;;;;Alcian Yellow Bactrim;;;;;Alecensa Bloodhound;;;;;Alecensis Bondronat;;;;;Alectinib Bonviva;;;;;Aleglitazar Carvedilol;;;;;Aleglitazar CellCept;;;;;ALK Cellcounting;;;;;Alkaline Phosphatase
Medical and Biological terms 454 Sequencing GS junior;; ärzte ohne grenzen;; ABP 215 ABP 215;; ABP 980 ABP 980;; ABP798 ABP798;; abstossungsreaktion* abstossungsreaktion*;; access to medicine access to medicine;; access to medicines access to medicines;; accuchek;; Accutrend;; acne acne;; adh adiposita* adiposita*;; Adipositas Adipositas;;
Roche Brands
NOT Thorsten Roche NOT Otto Roche NOT Liza Roche NOT Marc Roche NOT Donald Roche NOT Brandon Roche NOT Erick Roche NOT Dick Roche
Roche Products CETP inhibitor (R1658);;;;;ALT/GPT CINtec;;;;;Ammonia CoaguChek;;;;;Amphetamines Coasys;;;;;AmpliChip Cobas;;;;;AmpliChip cobimetinib;;;;;AmpliCor Combur-Test;;;;;AmpliCor Copegus;;;;;Amylase Cotellic;;;;;anaprox Crenezumab;;;;;Anti Muellerian Hormone Cymevene;;;;;Anti-CCP Dalcetrapib;;;;;Anti-HAV Danoprevir;;;;;Anti-HBc Dormicum;;;;;Anti-HBe Dual ISH test;;;;;Anti-HBs Elecsys;;;;;Anti-HCV emicizumab;;;;; emtansine;;;;;anti-HCV Immunoassay Epogin;;;;;anti-HCV Immunoassay Erivedge;;;;;Anti-Tg Esbriet;;;;;Anti-TPO Euglucon;;;;;Anti-TSH-R Fortovase;;;;;Apolipoprotein A1 Fuzeon;;;;;Apolipoprotein B Ganciclovir;;;;;ASLO Gantenerumab;;;;;AST/GOT
NOT Ella Roche
Gazyva;;;;;AT III
NOT Henri-Pierre Roche
Obinutuzumab;;;;;Atezolizumab
NOT Schriftsteller Roche
Gazyvaro;;;;;Avastin
NOT Schriftstellerin Roche Swisslab Sysmex
GDC-0425;;;;;Bactrim GDC-0449;;;;;Barbiturates GS FLX;;;;;Basel cell cocktail Herceptin;;;;;bcl-2 Invirase;;;;;Bicarbonate (CO2) iScan;;;;;Bilirubin
NOT Brian Roche NOT Mr. Roche NOT roche posay NOT roche brothers NOT daniel roche NOT Roche Football NOT La Roche Vendée Football NOT La Roche VF NOT Stephanie Roche NOT Cullen Roche NOT Charlotte Roche NOT la roche team NOT Dan Roche NOT Daniel Roche NOT Casy Roche NOT Travis Roche NOT Christof Roche NOT Nicolas Roche
Medical and Biological terms adrenalin insufficiencies advanced renal failure aids prevention aids prevention;; aids project aids project;; aids projects aids projects;; aids projekt aids projekt;; aids projekte aids projekte;; AIDS-Test AIDS-Test;; airway obstruction Akne akne* akne*;; Akne;; Alecensis;; Alectinib;; Aleglitazar;; Alzheimer Alzheimer* alzheimer*;; Alzheimer;; amerikanische arzneimittelbehörde amerikanische arzneimittelbehörde;; amerikanische gesundheitsbehörde amerikanische gesundheitsbehörde;; AmpliChip;; AmpliCor;; Anaemia Anaemia;; anemia
Roche Brands
Roche Products Kadcyla;;;;;blood screening Klonopin;;;;;Bloodhound Kytril;;;;;Bloodhound Lariam;;;;;Bondronat Lebrikizumab;;;;;Bonviva Lexotanil;;;;;BRAF Liat;;;;;C3c LightCycler;;;;;CA Lucentis;;;;;Ca2+ Mabthera;;;;;Calcitonin Madopar;;;;;Calcium Metmab;;;;;Cannabinoids Mircera;;;;;CARDIAC reader MPDL3280A;;;;;Carvedilol MPD-L3280;;;;;CD30 Multiplate;;;;;CEA Neorecormon;;;;;CellCept Neupogen;;;;;Cellcounting Neutrogin;;;;;Cellcounting Nimblegen;;;;;Ceruloplasmin NT-proBNP;;;;;CETP inhibitor (R1658) Nutropin;;;;;Chagas4 Ocrelizumab;;;;;Chloride Ocrevus;;;;;Cholinesterase Acetyl Olesoxime;;;;;Cholinesterase Butyryl Omalizumab;;;;;CINtec Pathway;;;;;CINtec Pegasys;;;;;CK Perjeta;;;;;CK-MB Pertuzumab;;;;;CMV Posicor;;;;;CMV IgG Pulmozime;;;;;CoaguChek Raptiva;;;;;CoaguChek Reflotron;;;;;Coagu-Chek Rituxan;;;;;Coasys Roactemra;;;;;Coasys rocaltrol;;;;;Cobas Rocephin;;;;;Cobas roferon;;;;;Cobas HPV
Medical and Biological terms anti-ABeta-MAb anti-ABeta-MAb;; antibioti* antibioti*;; antibiotic antibiotic;; Antibiotik* Antibiotik*;; Antibody detection Anticoagulation self monitoring anti-HCV Immunoassay;; antikörp* antikörp*;; antiretroviral antiretroviral;; anxiety Applied Science Applied Science;; arthritis Ärzte ohne grenzen asphyxia Assays asthma atezolizumab;; atrial fibrilation Atypical Ductal Hyperplasia Aufsichtsbehörde* Aufsichtsbehörde*;; auslaufend* Patent* auslaufend* Patent*;; autism autism* autism*;; autoimmun* autoimmun*;; autoimmune disease* Autoimmunkrankheit* Autoimmunkrankheit*;; BACE inhibitor
Roche Brands
Roche Products Rohypnol;;;;;cobimetinib Septifast;;;;;COHb Symphony Test;;;;;Combur-Test T-5224;;;;;Combur-Test T-DM1;;;;;Congo Red Tamiflu;;;;;Copegus TaqScreen;;;;;Cortisol Tarceva;;;;;Cotellic Tasmar;;;;;C-Peptide Taspoglutide;;;;;Creatinine Tecentriq;;;;;Crenezumab TG4001;;;;;CRP Tina-quant;;;;;CT NG TNKase;;;;;CTNG toradol;;;;;Cyfra 21-1 Troptonin;;;;;Cymevene Urisys;;;;;Cystatin C Valcyte;;;;;Cytomegalovirus Valganciclovir;;;;;Dalcetrapib Valium;;;;;Danoprevir Vantage;;;;;D-Dimer venetoclax;;;;;DHEA-S vesanoid;;;;;Diastase Viracept;;;;;Digitoxin Xcelligence;;;;;Digoxin Xeloda;;;;;Dormicum Xenical;;;;;Dual ISH test Xolair;;;;;Dual ISH test Zelboraf;;;;;EGFR Zenapax;;;;;Elastic staining kit Acid phosphatase;;;;;Elecsys ACTH;;;;;Elecsys AFB III;;;;;emtansine AFP;;;;;Epogin Alcian Blue;;;;;ER Alcian Yellow;;;;;ERG ALK;;;;;Erivedge Alkaline Phosphatase;;;;;Erythroccytes (Hb) ALT/GPT;;;;;Esbriet
Medical and Biological terms BACE inhibitor;; bakterielle Infektion* bakterielle Infektion*;; basal cell carcinoma BCD-022 BCD-022;; betablocker Betablocker* Betablocker*;; betablocker;; BI 695500 BI 695500;; BI 695502 BI 695502;; big pharma big pharma;; Biogeneric Biogeneric;; Biogenerico Biogenerico;; Biogenerika Biogenerika;; Biogenerikum Biogenerikum;; biogénérique biogénérique;; biol* biol*;; biologic copy biologic copy;; biologisch* Arznei* biologisch* Arznei*;; Biopharma* Biopharma*;; Biopharmazeutika Biopharmazeutika;; Biopharmazeutikum Biopharmazeutikum;; Biopharmazeutische Innovationen
Roche Brands
Roche Products Ammonia;;;;;Estradiol Amphetamines;;;;;Ethanol Amylase;;;;;Euglucon Anti Muellerian Hormone;;;;;Ferritin Anti-CCP;;;;;Folate Anti-HAV;;;;;Fortovase Anti-HBc;;;;;Fructosamine Anti-HBe;;;;;FSH Anti-HBs;;;;;FT3 Anti-HCV;;;;;FT4 Anti-Tg;;;;;Fuzeon Anti-TPO;;;;;Gamma Glutamyl Transferase Anti-TSH-R;;;;;Ganciclovir Apolipoprotein A1;;;;;Gantenerumab Apolipoprotein B;;;;;Gazyva ASLO;;;;;Gazyvaro AST/GOT;;;;;GDC-0425 AT III;;;;;GDC-0425 Barbiturates;;;;;GDC-0449 Basel cell cocktail;;;;;GDC-0449 bcl-2;;;;;GGT Bicarbonate (CO2);;;;;Giemsa Bilirubin;;;;;Glutamate Dehydrogenase blood screening;;;;;GMS III BRAF;;;;;GOT (AST) C-Peptide;;;;;GPT (ALT) C3c;;;;;Gram staining kit CA;;;;;GS FLX Ca2+;;;;;GS FLX Calcitonin;;;;;H&E Calcium;;;;;Haptoglobin Cannabinoids;;;;;Harmony test CD30;;;;;HbA1c CEA;;;;;HBeAg Ceruloplasmin;;;;;HBsAG Chagas4;;;;;HBV Chloride;;;;;hCG Cholinesterase Acetyl;;;;;HCV
Medical and Biological terms Biopharmazeutische Innovationen;; biosimilaire biosimilaire;; Biosimilar Biosimilar;; Biotech* Biotech*;; Bioterapeutico Bioterapeutico;; Biotherapeutic biotherapeutic copy biotherapeutic copy;; Biotherapeutic;; Biotherapeutika Biotherapeutika;; Biotherapeutikum Biotherapeutikum;; bladder cancer blockage of endotrachial tube Blood Gas and Electrolytes Blood glucose monitoring blood loss Blood sampling Blood sampling;; blood screening blood screening;; blood transfusion Blood-Bank Blood-Bank;; Bloodhound;; Blue genes Blue genes;; Blutbank Blutbank;; Blutgerinnungsmessgeraet Blutgerinnungsmessgeraet;; Blutgewinnung Blutgewinnung;;
Roche Brands
Roche Products Cholinesterase Butyryl;;;;;HDL CK;;;;;HE4 CK-MB;;;;;Hematocrit CMV;;;;;Hemoglobin total CMV IgG;;;;;HER-2 COHb;;;;;Herceptin Congo Red;;;;;hGH Cortisol;;;;;HHb Creatinine;;;;;HIV CRP;;;;;Homocysteine CT NG;;;;;HPV CTNG;;;;;HSV-1 IgG Cyfra 21-1;;;;;HSV-2 IgG Cystatin C;;;;;HTLV.(II|IV|I|1|2|4) Cytomegalovirus;;;;;Human papiloma virus DDimer;;;;;Humanpapilomavirus DHEA-S;;;;;Hydroxybutyrat Dehydrogenase Diastase;;;;;α1-Acid Glycoprotein Digitoxin;;;;;α1-Antitrypsin Digoxin;;;;;β 2-Microglobulin EGFR;;;;;β-CrossLaps Elastic staining kit;;;;;IgA ER;;;;;IgE ERG;;;;;IgG Erythroccytes (Hb);;;;;IgM Estradiol;;;;;Immunglobulin Ethanol;;;;;Interleukin 6 Ferritin;;;;;Invirase Folate;;;;;Iron Binding Capacity Unsaturated Fructosamine;;;;;iScan FSH;;;;;Jones FT3;;;;;K+ FT4;;;;;Kadcyla Gamma Glutamyl Transferase;;;;;Kappa light chains GGT;;;;;Ketone
Medical and Biological terms Blutglukose Blutglukose;; Blutscreening Blutscreening;; Bluttest Bluttest;; Blutzucker Blutzucker Messgerät;; Blutzucker Messgerät Blutzucker;; bone bonemarkers brain trauma breast cancer bronchitis BSE BSE;; Bundesamt für Gesundheit Bundesamt für Gesundheit;; cancer diagnostics cancer diagnostics;; cancer immunotherap* carbon monoxide poisoning Cardiac CARDIAC reader;; Cardiac testing Cardiac-reader Cardiac-reader;; Cellcounting;; Cell-free DNA central nervous system central nervous system;; cervical cancer cfDNA checkpoint inhibitor
Roche Brands
Roche Products Giemsa;;;;;Ki-67 Glutamate Dehydrogenase;;;;;Klonopin GMS III;;;;;KRAS GOT (AST);;;;;Kytril GPT (ALT);;;;;Lactate Gram staining kit;;;;;Lactate Dehydrogenase H&E;;;;;Lambda light chains Haptoglobin;;;;;Lariam Harmony test;;;;;LDL HbA1c;;;;;Lebrikizumab HBeAg;;;;;Leukocytes HBsAG;;;;;Lexotanil HBV;;;;;LH hCG;;;;;Liat HCV;;;;;LightCycler HDL;;;;;LightCycler HE4;;;;;Lipase Hematocrit;;;;;Lipids Hemoglobin total;;;;;Lipoprotein (a) HER-2;;;;;LSD hGH;;;;;Lucentis HHb;;;;;Mabthera HIV;;;;;Madopar Homocysteine;;;;;Magnesium HPV;;;;;Methadone HSV-1 IgG;;;;;Methaqualone HSV-2 IgG;;;;;MetHb HTLV.(II|IV|I|1|2|4);;;;;Metmab Human papiloma virus;;;;;Mircera Humanpapilomavirus;;;;;MPDL3280 Hydroxybutyrat Dehydrogenase;;;;;MPDL3280A IgA;;;;;Mucicarmine IgE;;;;;Multiplate IgG;;;;;Multiplex IgM;;;;;Myoglobin Immunglobulin;;;;;Na+ Interleukin 6;;;;;Neorecormon
Medical and Biological terms chelators Chemotherapie Chemotherapie;; chronic cardiac failure chronic hypermatremia Chronic progressing alveolar destruction Chronic renal failure CINtec;; Circle of care Circle of care;; Circulatory failure CLIA lab CLIA waiver Clinical Chemistry clinical trial* clinical trial*;; CNS CNS;; COAD CoaguChek;; Coagu-Chek;; Coagulation Coagulation monitoring Coasys;; Cobas HPV;; Cobas;; cognitive disorders cognitive disorders;; colitis Colorectal cancer Combur-Test;; conference conference;; Congenital Heart defect Congestive heart failure congress congress;;
Roche Brands
Roche Products Iron Binding Capacity Unsaturated;;;;;Neupogen Jones;;;;;Neutrogin K+;;;;;Nimblegen Kappa light chains;;;;;Nitrite Ketone;;;;;N-MID Osteocalcin Ki-67;;;;;NSE KRAS;;;;;NT-proBNP Lactate;;;;;NT-proBNP Lactate Dehydrogenase;;;;;NTproBNP Lambda light chains;;;;;Nutropin LDL;;;;;O2Hb Leukocytes;;;;;Obinutuzumab LH;;;;;Ocrelizumab Lipase;;;;;Ocrevus Lipids;;;;;Olesoxime Lipoprotein (a);;;;;Omalizumab LSD;;;;;Opiates Magnesium;;;;;Oxycodone Methadone;;;;;Oxygen Saturation Methaqualone;;;;;p16 MetHb;;;;;p18 Mucicarmine;;;;;P1NP Multiplex;;;;;PAP smear Myoglobin;;;;;parvovirus N-MID Osteocalcin;;;;;PAS Na+;;;;;Pathway Nitrite;;;;;PCO2 NSE;;;;;Pegasys NT-proBNP;;;;;Perjeta O2Hb;;;;;Pertuzumab Opiates;;;;;pH Oxycodone;;;;;Phencyclidine Oxygen Saturation;;;;;Phosphorus p16;;;;;PO2 p18;;;;;Posicor P1NP;;;;;Potassium
Medical and Biological terms continuous monitoring continuous monitoring;; COPD copia de producto biologico;; copia de producto bioterapeutico copia de producto bioterapeutico;; copie de médicament biologique;; copie de médicamentbiologique copie de produit biologique copie de produit biologique;; Corticosteroid excess Crenezumab;; crispr critical care Crohn's disease CT-P10 CT-P10;; CT-P6 CT-P6;; Cytotoxic agent administration DAT Decreeased blood volume Depression depression* depression*;; Depression;; dermatitis dermatolo* dermatolo*;; Dermatologie Dermatologie;; Dermatology Dermatology;; Dermatopathology diabet* diabet*;;
Roche Brands
Roche Products PAP smear;;;;;PR parvovirus;;;;;Prealbumin PAS;;;;;Procalcitonin PCO2;;;;;Progesterone pH;;;;;proGRP Phencyclidine;;;;;Prolactin Phosphorus;;;;;Propoxyphene PO2;;;;;PSA free Potassium;;;;;PSA total PR;;;;;PT/Quick Prealbumin;;;;;PTH Procalcitonin;;;;;Pulmozime Progesterone;;;;;Raptiva proGRP;;;;;Reflotron Prolactin;;;;;Reflotron Propoxyphene;;;;;Reticulum II PSA free;;;;;Rheumatoid factor PSA total;;;;;Rituxan PT/Quick;;;;;Roaccutan* PTH;;;;;Roactemra Reticulum II;;;;;rocaltrol Rheumatoid factor;;;;;Rocephin Rubella;;;;;roferon S-100;;;;;Rohypnol SCC4;;;;;Rubella sFlt-1/PlGF;;;;;S-100 SHBG;;;;;SCC4 SO2 COOX;;;;;Septifast Sodium;;;;;Septifast Soluble transferrin receptor;;;;;sFlt-1/PlGF Specific gravity;;;;;SHBG Steiner;;;;;SO2 COOX Steiner II;;;;;Sodium T-uptake;;;;;Soluble transferrin receptor T3;;;;;Specific gravity T4;;;;;Steiner Testosterone;;;;;Steiner II tHb-COOX;;;;;Swisslab Thyreoglobulin;;;;;Symphony Test
Medical and Biological terms Diabetes Diabetes mellitus Diabetes;; Diagnos* Diagnose Diagnose;; Diagnosis diagnosis of pleural effusion Diagnosis;; Diagnostic Diagnostic;; DIAGNOSTICS Diagnostics;; Diagnostik Diagnostik;; Diagnostika Diagnostika;; Digital pathology DISH Diuretic Issues DNA Dna Analyse Dna Analyse;; dna Chip dna Chip;; Dna Technologie Dna Technologie;; DNA;; Down Syndrome down syndrome;; Downs Syndrom dritte welt dritte welt;; Drug alterations Drug alterations - salicylate drug approval drug approval;; drug benefit drug benefit;;
Roche Brands
Roche Products Total Protein;;;;;Sysmex Toxo;;;;;T3 Toxoplasmosis;;;;;T4 TPLA (Syphilis);;;;;T-5224 Transferrin;;;;;Tamiflu Trichrome;;;;;TaqScreen Triglycerides;;;;;TaqScreen Triglycerides Glycerol blanked;;;;;Tarceva Troponin I;;;;;Tasmar Troponin T;;;;;Taspoglutide TSH;;;;;T-DM1 TTF 1;;;;;Tecentriq Urea (BUN);;;;;Testosterone Uric Acide;;;;;TG4001 Urobilinogen;;;;;tHb-COOX varicellazoster;;;;;Thyreoglobulin Viral load;;;;;Tina-quant Vitamin B12;;;;;Tina-quant Vitamin D;;;;;TNKase Vitamin D total;;;;;toradol α1-Acid Glycoprotein;;;;;Total Protein α1-Antitrypsin;;;;;Toxo β 2Microglobulin;;;;;Toxoplasmosis β-CrossLaps;;;;;TPLA (Syphilis) LightCycler;;;;;Transferrin Cellcounting;;;;;Trichrome 454 Sequencing GS junior;;;;;Triglycerides GS FLX;;;;;Triglycerides Glycerol blanked anti-HCV Immunoassay;;;;;Troponin I accuchek;;;;;Troponin T Dual ISH test;;;;;Troptonin GDC-0425;;;;;Troptonin GDC-0449;;;;;TSH Aleglitazar;;;;;TTF 1 Accutrend;;;;;T-uptake
Medical and Biological terms drug benefits drug benefits;; drug discovery drug discovery;; drug pipeline drug pipeline;; drug target* drug target*;; drugs drugs compan* drugs compan*;; drugs industry drugs industry;; drugs;; Dual ISH test;; Dyslipidemia Einlizenzierung* Einlizenzierung*;; eiweiss* eiweiss*;; Elecsys;; Emboli EMEA EMEA;; emergency room Emphysema Endocrinology Endrocrine disorders english keywords"Healthcare Entwicklungsländ* Entwicklungsländ*;; entzündung* entzündung*;; epidem* epidem*;;
Roche Brands
Roche Products AmpliChip;;;;;Urea (BUN) AmpliCor;;;;;Uric Acide CoaguChek;;;;;Urisys Coasys;;;;;Urisys Cobas;;;;;Urobilinogen Cobas HPV;;;;;Valcyte Combur-Test;;;;;Valganciclovir Elecsys;;;;;Valium NT-proBNP;;;;;Vantage Septifast;;;;;varicella-zoster TaqScreen;;;;;venetoclax Troptonin;;;;;vesanoid CARDIAC reader;;;;;Viracept Bloodhound;;;;;Viral load CINtec;;;;;Vitamin B12 Coagu-Chek;;;;;Vitamin D Reflotron;;;;;Vitamin D total Swisslab;;;;;Xcelligence Sysmex;;;;;Xeloda Tina-quant;;;;;Xenical Urisys;;;;;Xolair (Confirm|Inform|Modular|Path way|Multiplate).{1 Alecensis;;;;;Zenapax Alectinib;;;;;
Medical and Biological terms Europäische Arzneimittelagentur Europäische Arzneimittelagentur Europäische Arzneimittelagentur;; Europäische Arzneimittelagentur;; European Medicines Agency European Medicines Agency;; Excess HCO3 administration Excessive insulin expiring patent* expiring patent*;; F&E F&E;; FDA FDA Approval FDA;; Fertility fettleibig* fettleibig*;; fettleibigkeit fettleibigkeit;; fibrosis filing for approval filing for approval;; FISH flu flu;; Follow-on biologic Follow-on biologic;; forsch* forsch*;; Forschung & Entwicklung Forschung & Entwicklung;; Forschungsabteilung Forschungsabteilung;; Forschungsaufwendung* Forschungsaufwendung*;; Forschungslabor Forschungslabor;;
Roche Brands
Roche Products
Medical and Biological terms fragile-X fragile-X;; GABA-A GABA-A;; GABA-Alpha-5-inverse agonist GABA-Alpha-5-inverse agonist;; GDC-0425;; GDC-0449;; gefässerk* gefässerk*;; Gefässerkrankung* Gefässerkrankung*;; gefässkrank* gefässkrank*;; genanaly* genanaly*;; Gene expressing research Gene expressing research;; generic cop* generic cop*;; generics generics;; Generika* Generika*;; Generikum* Generikum*;; genet* genet*;; genetic test genetic test;; genmaterial genmaterial;; Genome sequencer Genome sequencer;; Genomics genomics;; genotyping Gentechnisch Gentechnisch;; Gentest gentest* gentest*;;
Roche Brands
Roche Products
Medical and Biological terms Gentest;; gentherap* gentherap*;; gesundheit* gesundheit*;; Gesundheitsmarkt* Gesundheitsmarkt*;; Gesundheitswesen Gesundheitswesen;; GI absobtive issues glaucoma glioblastoma glucose meter glucose meter;; GP 2013 GP 2013;; GP2013 GP-2013 GP2013;; GP-2013;; Grippe Grippe;; Grosslabor Grosslabor;; GS FLX;; H1N1 H1N1;; H5N1 H5N1;; HBV HBV;; HCV HCV;; Health care Health care;; HEALTHCARE health-care Healthcare keywords;; Healthcare;; health-care;; Heart attack Heart Failure
Roche Brands
Roche Products
Medical and Biological terms heilmittelgesetz heilmittelgesetz;; hematology hematology analyzer hematology analyzer;; Hematopathology Hemostasis Hepatic Cirrhosis Hepatitis Hepatitis C Hepatitis C;; Hepatitis;; Hepatology HER2 positive Hercules Hercules;; herzinsuffizien* herzinsuffizien*;; herzinsuffizienz herzinsuffizienz;; Herz-Kreislauf herzkreislauf* herzkreislauf*;; Herz-Kreislauf;; Histology HIV HIV;; HIV-Infektion HIV-Infektion;; hmg hmg;; hyperbiliruninemia Hypermagnesemia Hyperosmolality Hyperparathyroidism Hyperphosphatemia Hyperventilation by mechanical ventilator Hypodipsia Hypomagnesemia Hypoparathyroidism
Roche Brands
Roche Products
Medical and Biological terms Hypoventilation by mechanical ventilator Hypoxemia Immonhistochemistry immune oncology immunoassays immunoassays;; Immunochemistry immun-onkologie immuno-oncology immunotherap* immunsuppressiv* immunsuppressiv*;; immuntherap* Impaired fuction of respiratory center In situ hybridization In vitro diagnostics Inadequate cardiac output indication indication;; indikation indikation;; Infectious Diseases Infektionskrankheit* Infektionskrankheit*;; Inflammation inflammation* inflammation*;; influenza infusion system infusion system;; Infusionssystem Infusionssystem;; In-licensing In-licensing;; Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen;; institut*
Roche Brands
Roche Products
Medical and Biological terms institut*;; institute Institute for Quality and Efficiency in Health Care Institute for Quality and Efficiency in Health Care;; institute;; insulin Insulin deficiency insulin;; Insulinoma Insulinpumpe Insulinpumpe;; integrated health care integrated health care;; integrated healthcare integrated healthcare;; integrierte Gesundheitslösung* integrierte Gesundheitslösung*;; Intended copy biologic Intended copy biologic;; intensive care internal bleeding Interpharma Interpharma;; In-vitro diagnostics In-vitro diagnostics;; IQWiG IQWiG;; ISH isoniazid isoniazid;; IVD kassenpflichtig* kassenpflichtig*;; Ketoacidosis Kidney (renal) function kidney cancer klinisch* klinisch* Studi* klinisch* Studi*;;
Roche Brands
Roche Products
Medical and Biological terms klinisch* Test* klinisch* Test*;; klinisch* Versuch* klinisch* Versuch*;; klinisch*;; Kombinationstherapie* Kombinationstherapie*;; kongress* kongress*;; Konsumentenschutz Konsumentenschutz;; krankenkas* krankenkas*;; krankenvers* krankenvers*;; Krankheiten des zentralen Nervensystems Krankheiten des zentralen Nervensystems;; Krankheitserkennung Krankheitserkennung;; krankheitversicherungsgesetz krankheitversicherungsgesetz;; Krebs Krebs;; Kreislaufinsuffizienz Kreislaufinsuffizienz;; kvg kvg;; labor* labor*;; Laboratory automation laboratory diagnostics laboratory diagnostics;; Lactate acidosis Lactate clearence langzeittherapie* langzeittherapie*;; Lanzette Lanzette;; Left ventricular failure Leukämie
Roche Brands
Roche Products
Medical and Biological terms Leukämie;; leukemia lightcycler LightCycler;; linear array Lipid testing Liquid biopsy Loss of bicarbonate Loss of hypertonoc fluids lung cancer lupus MabionCD20 MabionCD20;; macular degeneration Malignancy Managed laboratory services Managed services MAO-B inhibitor MAO-B inhibitor;; Markenmedikament* Markenmedikament*;; marker marker;; Markteinführung* Markteinführung*;; Massive hemolysis Mechanical heart valve medicaid medicaid;; medical medical;; médicament biologique non comparable;; médicament biologique;; médicament obtenus par biotechnologie;; médicamentbiologique médicamentbiologique non comparable médicamentobtenus par biotechnologie medicare medicare;;
Roche Brands
Roche Products
Medical and Biological terms medicine medicine* medicine*;; medicine;; Medicines and Healthcare products Regulatory Agency Medicines and Healthcare products Regulatory Agency;; medicins sans frontieres;; Medikament* Medikament*;; Medikamentenpreis* Medikamentenpreis*;; Medikamentenzulassung* Medikamentenzulassung*;; medizinische Formel medizinische Formel;; meilenstein Melanoma Metabolic Metabolic acidosis Metabolic Alkalosis Metabolic syndrome metabolism metabolism;; metasta* metasta*;; Metastase* Metastase*;; metastatic melanoma mGluR2 antagonist mGluR2 antagonist;; mGluR5 antagonist mGluR5 antagonist;; MHRA MHRA;; microarrays microarrays;; Microbiology milenstein;; milestone milestone;;
Roche Brands
Roche Products
Medical and Biological terms molecular diagnostics molecular diagnostics;; molecular entit* molecular entit*;; Molekulardiagnostik Molekulardiagnostik;; Monitoring Monitoring device Monotherapie* Monotherapie*;; multiple myeloma multiple sclerosis multiple sclerosis;; multiple sklerose multiple sklerose;; Myocardinal Infarction Nachahmerprodukt* Nachahmerprodukt*;; Nachfolgeprodukt Nachfolgeprodukt;; Nachfolgerprodukt* Nachfolgerprodukt*;; National Institute for Health and Care Excellence National Institute for Health and Care Excellence;; NCB NCB;; near patient testing near patient testing;; Nebenwirkung* Nebenwirkung*;; neoteben neoteben;; nephrotic syndrome neue* Medikament* neue* Medikament*;; neurodegenerati* neurodegenerati*;; Neuromuscular disease new medicine* new medicine*;;
Roche Brands
Roche Products
Medical and Biological terms next generation sequencing NGOs NGOs;; NGS NICE NICE;; nichtstaatliche Organisationen nichtstaatliche Organisationen;; NimbleGen;; nipt non small cell lung cancer Non-comparable biotherapeutic product Non-comparable biotherapeutic product;; Non-Hodgkin-Lymphom Non-Hodgkin-Lymphom;; non-Hodgkin's lymphom* non-invasive prenatal test NT-proBNP;; nydrazid nydrazid;; obesit* obesit*;; obesity obesity;; Obstructive ling disease occult blood testing occult blood testing;; ocular hypertension Oncology Oncology;; onkologi* onkologi*;; Onkologie Onkologie;; open heart surgery organtransplantation* organtransplantation*;; Osteaoporosys osteopor* osteopor*;;
Roche Brands
Roche Products
Medical and Biological terms osteoporose osteoporose;; ostheopor* ostheopor*;; OTC-Produkt* OTC-Produkt*;; ovarian cancer oxfam oxfam;; oxygen transport Panceatitis pancreatic cancer pandemi* pandemi*;; parallel import parallel import;; parallel imports parallel imports;; Parallelimport Parallelimport;; Parallelimporte Parallelimporte;; Parkinson* Parkinson*;; patent filing* patent filing*;; patent lawsuit* patent lawsuit*;; patent protection patent protection;; patent ruling* Patentablauf* Patentablauf*;; Patentantr* Patentantr*;; Patententscheid* Patententscheid*;; Patentschutz Patentschutz;; Patentstreit* Patentstreit*;; Pathology
Roche Brands
Roche Products
Medical and Biological terms Pathway;; patient patient advocacy group patient advocacy group;; patient advocacy groups patient advocacy groups;; patient organisation patient organisation;; patient organisations patient organisations;; patient;; Patienten* Patienten*;; Patientenorganisation* Patientenorganisation*;; patients patients;; PCR PCR;; peptid* peptid*;; personalisierte Medizin personalisierte Medizin;; PF-05280014 PF-05280014;; PF-05280586 PF-05280586;; PF-06439535 PF-06439535;; PHARMA pharma access pharma access;; pharma compan* pharma compan*;; pharma giant pharma giant;; Pharma keywords;; pharma sector pharma sector;; Pharma* Pharma*;; pharmaaccess
Roche Brands
Roche Products
Medical and Biological terms pharmaaccess;; Pharmacogenomic Pharmacogenomic;; Pharmaverband Pharmaverband;; PhRMA PhRMA;; pipeline pipeline;; Plasmascreening Plasmascreening;; Plasmatest Plasmatest;; Point of Care Point testing Point testing;; Polydipsia polymerase chain reaction polymerase chain reaction;; Potassium depletion Prediction Predisposition Preeclampsia pregnancy care Preiskontrolle Preiskontrolle;; Preisreduktion Preisreduktion;; Preisregulierung Preisregulierung;; Preissenkung* Preissenkung*;; prescription drug costs prescription drug costs;; Prevention price control price control;; Primary Staining Producto bioterapeutico no comparable Producto bioterapeutico no comparable;;
Roche Brands
Roche Products
Medical and Biological terms produits biologiques noncomparables produits biologiques noncomparables;; produits biologiques successeurs produits biologiques successeurs;; Prostate cancer protein* protein*;; Proteomics Proteomics;; Psoriasis Psoriasis;; pulmonary disease Pulmonary embolisme Pulmonary fibrosis Pulmonary Oedema r&d r&d;; Reagents Recherche et développement Recherche et développement;; Referrence labs Reflotron;; reimbursement reimbursement;; Renal renal cell cancer Renal failure Renal tubular acidosis research Research & development Research & development;; research department* research department*;; research lab* research lab*;; research laborator* research laborator*;; research process research process;;
Roche Brands
Roche Products
Medical and Biological terms research;; Respiratory Acidosis Respiratory Alkalosis Respiratory depression rezeptfrei* rezeptfrei*;; rezeptpflichtig* rezeptpflichtig*;; RG7800 RG7800;; rheumatoid arthritis rheumatoide arthritis rheumatoide arthritis;; rimifon rimifon;; risk prediction risk prediction;; RNA RNA;; rückerstattung rückerstattung;; Rückruf eines Medikamentes Rückruf eines Medikamentes;; Rx-drugs Rx-drugs;; Salt-losing neuropathies santesuisse santesuisse;; SB3 SB3;; schizophreni* schizophreni*;; schizophrenia* schizophrenia*;; Schizophrenie Schizophrenie;; SCIENCE Science keywords;; scientif* scientif*;; Screening Screening programs
Roche Brands
Roche Products
Medical and Biological terms Selbstdiagnose Selbstdiagnose;; Self monitoring Sepsis Septic shock Septicemia Septifast;; Serology Serum Work Area Severe hemorrhage Severe hyperlipidemia Shunt of venous blood to arterial system skin cancer SMA SMA;; spanish keywords"copia de producto biologico Special Stains Specimen workflow spinal muscular atrophy spinal muscular atrophy;; stammzell* stammzell*;; standardized blood test or diabetes Stechhilfe Stechhilfe;; stem cell* stem cell*;; stoffwechselkrank* stoffwechselkrank*;; stoffwechselkrankheit* stoffwechselkrankheit*;; Stratification Stress Stroke studie studie;; study study;; Swisslab;;
Roche Brands
Roche Products
Medical and Biological terms Swissmedic Swissmedic;; Syphilis Sysmex;; TaqScreen;; TDM therap* therap*;; Therapie* Therapie*;; Therapiegebiet*;; Therapy Therapy;; tierexperim* tierexperim*;; tierversuch* tierversuch*;; Tina-quant;; Tissue Diagnostics Tissue Diagnostics;; Tissue oxygenation Tissue perfusion TORCH Transplantationsmedizin transplantationsmedizin* transplantationsmedizin*;; Transplantationsmedizin;; TRIPS TRIPS;; Troptonin;; tuber?ulos* tuber?ulos*;; tumor Tumor markers Tumor* Tumor*;; tumormarkers unaids unaids;; Urine Urisys;; urogenital*
Roche Brands
Roche Products
Medical and Biological terms urogenital*;; Urogenitalerkrankung* Urogenitalerkrankung*;; V1 receptor antagonist V1 receptor antagonist;; Value of diagnostics vasculitis Vasoconstriction Venous thromboembolism Venous tromboembolism virenstam* virenstam*;; Virenstamm Virenstamm;; virologi* virologi*;; Virologie Virologie;; virology virology;; Virus Virus;; Vitamin D defect Vitamin D deficiency Vogelgrippe Vogelgrippe;; Water balance West Nile Virus West Nile Virus;; WHO;; Wirkstoff* Wirkstoff*;; wissenschaft* wissenschaft*;; Women's Health Workflow consulting world trade organisation world trade organisation;; ZNS ZNS;; Zulassungsanmeldung* Zulassungsanmeldung*;;
Roche Brands
Roche Products
Medical and Biological terms Zulassungsbehörde* Zulassungsbehörde*;; Zulassungsverfahren* Zulassungsverfahren*;; "Thema Patente: englische Begriffe"patent ruling*;; *genom* *genom*;; *grippe* *grippe*;; *hodgkin lymphom* *hodgkin lymphom*;; *infektion* *infektion*;; *krankheit* *krankheit*;; *krebs* *krebs*;; *nervensystem* *nervensystem*;; *therapie* *therapie*;; *tumor* *tumor*;; *wirkstoff* *wirkstoff*;;
