System, Baltimore (M.-C. Roghmann); and US Food and Drug. Administration ... MRSA infection (7â9), non-US populations (10â12), or ...... 2007;13:1840â6. 24.
Staphylococcus aureus Infections in US Veterans, Maryland, USA, 1999–20081 LaRee A. Tracy, Jon P. Furuno, Anthony D. Harris, Mary Singer, Patricia Langenberg, and Mary-Claire Roghmann
MedscapeCME ACTIVITY Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the ACCME to provide continuing medical education for physicians. Medscape, LLC designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test and/or complete the evaluation at www.medscape.org/journal/eid; (4) view/print certificate. Release date: February 25, 2011; Expiration date: February 25, 2012 Learning Objectives Upon completion of this activity, participants will be able to: •
Describe the change in overall incidence of S. aureus infections between fiscal years 1999 and 2008 based on a retrospective cohort study using patient-level data in the Veterans Affairs Maryland Healthcare System
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Describe trends in invasive vs noninvasive S. aureus infections, changes in methicillin susceptibility, and changes in location of onset and infection site between fiscal years 1999 and 2008 based on the aforementioned study
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Describe hospital infection-control practices that may contribute to declining incidence of invasive S. aureus infections
Editor Karen L. Foster, MA, Technical Writer/Editor, Emerging Infectious Diseases. Disclosure: Karen L. Foster, MA, has disclosed no relevant financial relationships. CME Author Laurie Barclay, MD, freelance writer and reviewer, Medscape, LLC. Disclosure: Laurie Barclay, MD, has disclosed no relevant financial relationships. Authors Disclosures: LaRee A. Tracy, MA, PhD; Jon P. Furuno, PhD; Mary Singer, PhD, MD; Patricia Langenberg, PhD; and Mary-Claire Roghmann, MD, MS, have disclosed no relevant financial relationships. Anthony D. Harris, MD, MPH, has disclosed the following relevant financial relationship: served as an advisor or consultant for Ansell on a retrospective database project.
Trends in Staphylococcus aureus infections are not well described. To calculate incidence in overall S. aureus infection and invasive and noninvasive infections according to methicillin susceptibility and location, we conducted a 10-year population-based retrospective cohort study (1999–2008) using patient-level data in the Veterans Affairs Author affiliations: University of Maryland, Baltimore, Maryland, USA (L.A. Tracy, J.P. Furuno, A.D. Harris, P. Langenberg, M.C. Roghmann); Veterans Administration Maryland Health Care System, Baltimore (M.-C. Roghmann); and US Food and Drug Administration, Silver Spring, Maryland, USA (M. Singer) DOI: 10.3201/eid1703.100502
Maryland Health Care System. We found 3,674 S. aureus infections: 2,816 (77%) were noninvasive; 2,256 (61%) were methicillin-resistant S. aureus (MRSA); 2,517 (69%) were community onset, and 1,157 (31%) were hospital onset. Sixty-one percent of noninvasive infections were skin and soft tissue infections; 1,112 (65%) of these were MRSA. Ten-year averaged incidence per 100,000 veterans was 749 (± 132 SD, range 549–954) overall, 178 (± 41 SD, range 114–259) invasive, and 571 (± 152 SD, range 364–801) noninvasive S. aureus infections. Incidence of all 1 This study was presented in part at the 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; 2009 Sep 11–15; San Francisco, California, USA (abstracts 1217 and 3136).
Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 17, No. 3, March 2011
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S. aureus infections significantly increased (p
