Acta Neurobiol. Exp. 2002, 62: 19-24
Superior laryngeal nerve section abolishes capsaicin evoked chemoreflex in anaesthetized rats Katarzyna Kaczyñska and Ma³gorzata Szereda-Przestaszewska Laboratory of Respiration Physiology, Department of Neurophysiology, Medical Research Centre Polish Academy of Sciences, 5 Pawiñskiego St., 02-106 Warsaw, Poland, Email:
[email protected]
Abstract. Respiratory effects of an intravenous injection of capsaicin were investigated in nine vagotomized and subsequently laryngeally deafferentated, urethane- and chloralose- anaesthetized and spontaneously breathing rats. Bolus injection of capsaicin (5 mg/kg) into the right femoral vein induced an expiratory apnoea of 4.23 ± 0.63 s duration (mean ± SEM). In post-apnoeic breathing, tidal volume increased by 14% from the control level (P
