Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate). Human Delta Catenin ..... Proto-oncogene tyrosine-protein kinase Src (p60-Src).
Table S1.1. NOS family. Abbrevietion At NADPH-like Os NADPH-like Dicty NADPH-like Yeast NADPH-like Sponge NOS-like Sponge NADPH-like Fly NOS Fly NADPH Human nNOS Human eNOS Human iNOS Human NADPH
gi 7269302 50942815 66799961 730126 N.A. N.A. 26006989 12643739 1709333 266648 1352513 2851393
Swissprot Locus N.A. N.A. N.A. NCPR_YEAST N.A. N.A. NOS_DROME NCPR_DROME NOS1_HUMAN NOS3_HUMAN NOS2A_HUMAN NCPR_HUMAN
Description NADPH-ferrihemoprotein reductase ATR1 putative cytochrome P450 reductase sulfite reductase (NADPH) NADPH--cytochrome P450 reductase (CPR) (P450R) N.A. N.A. CG6713 Nitric-oxide synthase (dNOS) CG11567 NADPH--cytochrome P450 reductase (CPR) (P450R) Nitric-oxide synthase, brain (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) Nitric-oxide synthase, endothelial (Endothelial NOS) (eNOS) Nitric oxide synthase, inducible (Inducible NOS) (iNOS) NADPH--cytochrome P450 reductase (CPR) (P450R)
Table S1.2. PMCA family. Abbrevietion At PMCA-like Os PMCA-like Dicty PMCA-like Yeast PMCA-like Sponge PMCA-like Fly PMCA Human PMCA1 Human PMCA2 Human PMCA3 Human PMCA4
gi 12643246 75322378 1703456 728904 N.A. 62473111 14286104 14286115 14286116 14286105
Swissprot Locus ACA8_ARATH ACA6_ORYSA ATC1_DICDI ATC2_YEAST N.A. N.A. AT2B1_HUMAN AT2B2_HUMAN AT2B3_HUMAN AT2B4_HUMAN
Description Putative calcium-transporting ATPase 11, plasma membrane-type Probable calcium-transporting ATPase 6, plasma membrane-type Probable calcium-transporting ATPase PAT1 Calcium-transporting ATPase 2 (Vacuolar Ca(2+)-ATPase) N.A. CG2165 Plasma membrane calcium-transporting ATPase 1 (PMCA1) Plasma membrane calcium-transporting ATPase 2 (PMCA2) Plasma membrane calcium-transporting ATPase 3 (PMCA3) Plasma membrane calcium-transporting ATPase 4 (PMCA4)
Table S1.3. CaMKII and CASK families. Abbrevietion At CaMK-like Os CaMK-like Dicty CaMK-like Yeast CaMK-like Sponge CaMKI-like Sponge CaMKII-like CN CASK-like Fly CaMKII Fly CaMKI Fly CaMGUK Human CaMKII alpha Human CaMKII beta Human CaMKII delta Human CaMKII gamma Human CaMKI alpha Human CaMKI beta Human CaMKI delta Human CaMKI gamma Human CASK
gi 12322336 50355719 1730055 2507190 N.A. N.A. N.A. 46576378 3893099 34223738 20177970 12643413 12643414 62512173 3122301 67466915 56404610 73620970 27735175
Swissprot Locus N.A. N.A. MYLK_DICDI KCC2_YEAST N.A. N.A. N.A. KCC2A_DROME N.A. CAKI_DROME KCC2A_HUMAN KCC2B_HUMAN KCC2D_HUMAN KCC2G_HUMAN KCC1A_HUMAN KCC1B_HUMAN KCC1D_HUMAN KCC1G_HUMAN CSKP_HUMAN
Description calcium-dependent protein kinase putative calcium-dependent protein kinase Myosin light chain kinase (MLCK) Calcium/calmodulin-dependent protein kinase II N.A. N.A. N.A. CG18069 Calcium/calmodulin-dependent protein kinase type II alpha chain CG1495 Calcium/calmodulin dependent protein kinase I CG6703 Calcium/calmodulin-dependent protein kinase (CaMGUK) Calcium/calmodulin-dependent protein kinase type II alpha chain Calcium/calmodulin-dependent protein kinase type II beta chain Calcium/calmodulin-dependent protein kinase type II delta chain Calcium/calmodulin-dependent protein kinase type II gamma chain Calcium/calmodulin-dependent protein kinase type 1 (CaM-KI) (CaM kinase I alpha) Calcium/calmodulin-dependent protein kinase type 1B(CaM kinase I beta) Calcium/calmodulin-dependent protein kinase type 1D (CaM kinase I delta) Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase I gamma) Peripheral plasma membrane protein CASK (hCASK)
Table S1.4. IP3R family. Abbrevietion Sponge IP3R-like Sponge RYR-like Fly IP3R Fly RYR Human IP3R1 Human IP3R2 Human IP3R3 Human RYR1 Human RYR2 Human RYR3
gi N.A. N.A. 44888998 456984 17366467 2833252 17366458 19857096 17380312 18202506
Swissprot Locus N.A. N.A. ITPR_DROME RY44_DROME ITPR1_HUMAN ITPR2_HUMAN ITPR3_HUMAN RYR1_HUMAN RYR2_HUMAN RYR3_HUMAN
Description N.A. N.A. CG1063 Inositol 1,4,5-trisphosphate receptor (InsP3 receptor) (InsP3R) CG10844 ryanodine receptor, calcium release channel Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5-trisphosphate receptor) Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5-trisphosphate receptor) Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5-trisphosphate receptor) Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3)
Table S1.5. Delta Catenin and Beta Catenin families. Abbrevietion At ARMC6-like Os ARMC6-like Dicty ARMC6-like Sponge p120/Delta Catenin-like Sponge Beta Catenin-like Fly Beta Catenin Fly Delta Catenin Fly ARMC6 Human p120 Catenin Human Delta Catenin Human Plakophilin1 Human Plakophilin2 Human Plakophilin3 Human p0071 Human ARVC Human Beta Catenin
gi 111074180 50913021 10444518 N.A. N.A. 114162 6959880 19922518 14916543 84028193 20138951 20139105 20139301 20139104 12229553 461854
Swissprot Locus N.A. N.A. N.A. N.A. N.A. ARM_DROME N.A. N.A. CTND1_HUMAN CTND2_HUMAN PKP1_HUMAN PKP2_HUMAN PKP3_HUMAN PKP4_HUMAN ARVC_HUMAN CTNB1_HUMAN
Description At4g33945 armadillo/beta-catenin repeat protein-like Aardvark N.A. N.A. CG11579 Armadillo segment polarity protein CG17484 Adherens junction protein p120 CG5721 Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) Plakophilin-1 (Band-6 protein) (B6P) Plakophilin-2 Plakophilin-3 Plakophilin-4 (p0071) Armadillo repeat protein deleted in velo-cardio-facial syndrome Beta-catenin
Human PLAK Human ARMC6
130257 109940304
PLAK_HUMAN ARMC6_HUMAN
Junction plakoglobin (Desmoplakin-3) (Desmoplakin III) Armadillo repeat-containing protein 6
Table S1.6. GKAP family. Abbrevietion Sponge GKAP/DLG7 CN GKAP-like CN DLG7-like Fly vulcan Fly mars Human GKAP1 Human GKAP2 Human GKAP3 Human GKAP4 Human DLG7
gi N.A. N.A. N.A. 24585883 20129953 18201963 71153507 71153509 18203629 82592583
Swissprot Locus N.A. N.A. N.A. N.A. N.A. DLGP1_HUMAN DLGP2_HUMAN DLGP3_HUMAN DLGP4_HUMAN DLG7_HUMAN
Description N.A. N.A. N.A. CG8390 vulcan CG17064 mars Disks large-associated protein 1 (DAP-1) (hGKAP) Disks large-associated protein 2 (DAP-2)(SAPAP2) Disks large-associated protein 3 (DAP-3) (SAPAP3) Disks large-associated protein 4 (DAP-4) (SAPAP4) Discs large homolog 7 (Hepatoma up-regulated protein) (HURP)
Table S1.7. SynGAP family. Abbrevietion Dicty GAP-like Yeast GAP-like Sponge GAP1 Sponge SynGAP-like (GAP2) Sponge GAP3 Fly GAP1 Fly SynGAP-like (GAP2) Fly GAP3 Human SynGAP Human NGAP Human RasP21-1 Human RasP21-2 Human RasP21-3 Human RasP21-4
gi 66816789 543907 N.A. N.A. N.A. 68067650 33112300 4107166 34098679 13959419 4506431 12545408 38201692 31745138
Swissprot Locus N.A. BUD2_YEAST N.A. N.A. N.A. GAP1_DROME GAP2_DROME N.A. SYGP1_HUMAN NGAP_HUMAN N.A. N.A. N.A. N.A.
Description NGAP-like protein Inhibitory regulator protein BUD2/CLA2 N.A. N.A. N.A. CG6721 GTPase-activating protein CG32560 Probable Ras GTPase-activating protein CG9209 vacuolar peduncle Ras GTPase-activating protein SynGAP Ras GTPase-activating protein nGAP RAS p21 protein activator 1 isoform 1 RAS p21 protein activator 2 RAS p21 protein activator 3 RAS p21 protein activator 4
Table S1.8. Cript family. Abbrevietion At Cript-like Os Cript-like Sponge Cript-like Fly Cript Human Cript
gi 15220607 50941887 N.A. 7297565 7661798
Swissprot Locus N.A. N.A. N.A. N.A. N.A.
Description unknown protein putative postsynaptic protein CRIPT N.A. CG4537 postsynaptic protein CRIPT
Table S1.9. Homer family. Abbrevietion Dicty VASP-like Sponge Homer-like Fly Homer Fly Enabled Human Homer1 Human Homer2 Human Homer3 Human Enabled Human VASP
gi 66804927 N.A. 3834623 24655476 38604765 38605067 38605068 48428086 1718079
Swissprot Locus N.A. N.A. N.A. N.A. HOME1_HUMAN HOME2_HUMAN HOME3_HUMAN ENAH_HUMAN VASP_HUMAN
Description vasodilator-stimulated phosphoprotein N.A. CG11324 homer CG15112 enabled Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Protein enabled homolog Vasodilator-stimulated phosphoprotein
Table S1.10. SPAR family. Abbrevietion Dicty RapGAP-like Sponge SPAR-like Sponge Rap1GAP-like Fly Rap1GAP Human SI1L1 (SPAR) Human SI1L2 Human SI1L3 Human Rap1GAP1 Human Rap1GAP2
gi 66802848 N.A. N.A. 2655096 50401319 85681894 50401326 1350590 51869679
Swissprot Locus N.A. N.A. N.A. N.A. SI1L1_HUMAN SI1L2_HUMAN SI1L3_HUMAN RGP2_HUMAN N.A.
Description hypothetical protein DDB0183944 N.A. N.A. CG33529 Rapgap1 Signal-induced proliferation-associated 1-like protein 1 Signal-induced proliferation-associated 1-like protein 2 Signal-induced proliferation-associated 1-like protein 3 Rap1 GTPase-activating protein 1 (Rap1GAP) Rap1 GTPase activating protein 2a
Table S1.11. Cortactin family. Abbrevietion Dicty SH3_Cortactin-like Yeast ABP1 Sponge Cortactin-like Fly Cortactin Human Cortactin Human HCLS1
gi 28828733 113000 N.A. 24648611 2498954 123557
Swissprot Locus N.A. ABP1_YEAST N.A. N.A. SRC8_HUMAN HCLS1_HUMAN
Description hypothetical protein Actin-binding protein N.A. CG3637 Cortactin Src substrate cortactin (Amplaxin) (Oncogene EMS1) Hematopoietic lineage cell-specific protein
Swissprot Locus GLR33_ARATH N.A. N.A. N.A. N.A.
Description Glutamate receptor 3.3 precursor (Ligand-gated ion channel 3.3) putative glutamate receptor G-protein-coupled receptor (GPCR) family protein N.A. N.A.
Table S1.12. Metabotropic GluR and GABAB Receptor families. Abbrevietion gi At GLR33 41017227 Os GLR 50904793 Dicty GABABR-like 60463477 Sponge mGluR-like(1) N.A. Sponge mGluR-like(2) N.A.
Sponge mGluR-like(3) Sponge mGluR-like(4) Sponge mGluR-like(5) Sponge mGluR-like(6) Sponge mGluR-like(7) Sponge mGluR-like(8) Sponge GABABR-like Fly GABABR 1 Fly GABABR 2 Fly GABABR 3 Fly mGluR Fly mGluXR Human GABABR 1 Human GABABR 2 Human mGluR 1 Human mGluR 2 Human mGluR 3 Human mGluR 4 Human mGluR 5 Human mGluR 6 Human mGluR 7 Human mGluR 8 Human CASR Human GPC6A Human TS1R 1 Human TS1R 2 Human TS1R 3
N.A. N.A. N.A. N.A. N.A. N.A. N.A. 13160942 13160945 24580689 17380359 42538965 12643873 12643641 62297775 76803802 76803803 2495077 1709020 3024134 2495078 12644040 1168781 74745292 57013075 57013086 62299063
N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. MGR_DROME N.A. GABR1_HUMAN GABR2_HUMAN MGR1_HUMAN MGR2_HUMAN MGR3_HUMAN MGR4_HUMAN MGR5_HUMAN MGR6_HUMAN MGR7_HUMAN MGR8_HUMAN CASR_HUMAN GPC6A_HUMAN TS1R1_HUMAN TS1R2_HUMAN TS1R3_HUMAN
N.A. N.A. N.A. N.A. N.A. N.A. N.A. CG15274 metabotropic GABA-B receptor subtype 1 CG6706 metabotropic GABA-B receptor subtype 2 CG3022 metabotropic GABA-B receptor subtype 3 CG11144 Metabotropic glutamate receptor CG30361 metabotropic X receptor GABA-B receptor 1 GABA-B receptor 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3
Table S1.13. PKC family. Abbrevietion At PKC-like Os PKC-like Dicty PKC-like Yeast PKC-like Sponge PKC1 Sponge PKC2 Sponge PKC3 Fly PKC1 Fly PKC2 Fly PKC3 Fly PKC4 Fly aPKC Human PKC delta Human PKC theta Human PKC eta Human PKC epsilon Human PKC beta Human PKC alpha Human PKC gamma Human PKC zeta Human PKC iota
gi 21431798 108707998 1730069 585365 N.A. N.A. N.A. 26006990 125543 125547 31340528 24653760 547803 20141582 1346393 400135 20141488 125549 462455 68067736 1170688
Swissprot Locus KPK19_ARATH N.A. KRAC_DICDI KPC1_YEAST N.A. N.A. N.A. KPC1_DROME KPC2_DROME KPC3_DROME KPC4_DROME N.A. KPCD_HUMAN KPCT_HUMAN KPCL_HUMAN KPCE_HUMAN KPCB_HUMAN KPCA_HUMAN KPCG_HUMAN KPCZ_HUMAN KPCI_HUMAN
Description Serine/threonine-protein kinase AtPK19 Serine/threonine-protein kinase AtPK19, putative, expressed RAC-family serine/threonine-protein kinase homolog Protein kinase C-like 1 (PKC 1) N.A. N.A. N.A. CG6622 Protein kinase C, brain isozyme (PKC) CG6518 Protein kinase C, eye isozyme (PKC) CG1954 Protein kinase C (PKC) (dPKC98F) CG10524 Putative protein kinase C, delta type homolog CG10261 atypical protein kinase C Protein kinase C delta type Protein kinase C theta type Protein kinase C eta type Protein kinase C epsilon type Protein kinase C beta type Protein kinase C alpha type Protein kinase C gamma type Protein kinase C zeta type Protein kinase C iota type
Table S1.14. Alpha Catenin family. Abbrevietion Dicty Vinculin-like Sponge Alpha Catenin-like Sponge Vinculin-like Fly Alpha Catenin Fly Alpha Catulin Fly Vinculin Human Alpha E-Catenin Human Alpha N-Catenin Human Alpha T-Catenin Human Alpha Catulin Human Vinculin
gi 66808591 N.A. N.A. 21264412 24762469 50401320 461853 14916980 78099215 62901512 21903479
Swissprot Locus N.A. N.A. N.A. CTNA_DROME N.A. VINC_DROME CTN1_HUMAN CTN2_HUMAN CTN3_HUMAN CTNL1_HUMAN VINC_HUMAN
Description putative actin binding protein N.A. N.A. CG17947 Catenin-alpha CG2987 alpha-catenin-related CG3299 Vinculin Alpha-1 catenin (Cadherin-associated protein) (Alpha E-catenin) Alpha-2 catenin (Alpha-catenin-related protein) (Alpha N-catenin) Alpha-3 catenin (Alpha T-catenin) (Cadherin-associated protein) Alpha-catulin (Catenin alpha-like protein 1) (Alpha-catenin-related protein) Vinculin (Metavinculin)
Table S1.15. Citron family. Abbrevietion At kinase_171888 At kinase_179637 Dicty kinase_642376 Sponge S_Tk1 Sponge Citron-like (S_Tk2) Sponge S_Tk3 Fly Citron Fly ROCK Fly MRCK Human Citron Human ROCK1 Human ROCK2 Human MRCKA
gi 15219591 15225358 66816743 N.A. N.A. N.A. 24663340 24642569 24762562 57015279 47605999 47605963 74746874
Swissprot Locus N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. CTRO_HUMAN ROCK1_HUMAN ROCK2_HUMAN MRCKA_HUMAN
Description kinase kinase putative protein serine/threonine kinase N.A. N.A. N.A. CG10522 CG9774 Rho-kinase CG4012 genghis khan Citron Rho-interacting kinase (CRIK) Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase MRCK alpha
Human MRCKB Human MRCKG Human DMPK
92090617 74762299 1706450
MRCKB_HUMAN MRCKG_HUMAN DMPK_HUMAN
Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase MRCK gamma Myotonin-protein kinase (Myotonic dystrophy protein kinase)
Table S1.16. Stargazin family. Abbrevietion Fly VD Calcium Channel-like Human VD Calcium Channel 2 (Stargazin) Human VD Calcium Channel 3 Human VD Calcium Channel 4 Human VD Calcium Channel 5 Human VD Calcium Channel 7 Human VD Calcium Channel 8
gi 71854527 6685289 6685277 10719940 20532390 51702249 20532017
Swissprot Locus N.A. CCG2_HUMAN CCG3_HUMAN CCG4_HUMAN CCG5_HUMAN CCG7_HUMAN CCG8_HUMAN
Description CG33670 Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-5 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit
Swissprot Locus N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. EGFR_DROME SRC42_DROME SRC64_DROME ABL_DROME FPS_DROME ROR2_DROME ROR1_DROME BTKL_DROME N.A. EPHB1_HUMAN EPHB2_HUMAN EPHB3_HUMAN EPHB4_HUMAN EPHB6_HUMAN EPHA1_HUMAN EPHA2_HUMAN EPHA3_HUMAN EPHA4_HUMAN EPHA5_HUMAN EPHA7_HUMAN EPHA8_HUMAN EPHAA_HUMAN SRC_HUMAN FRK_HUMAN FYN_HUMAN YES_HUMAN FGR_HUMAN HCK_HUMAN LCK_HUMAN LYN_HUMAN BLK_HUMAN SRMS_HUMAN ABL1_HUMAN ABL2_HUMAN FES_HUMAN FER_HUMAN ROR2_HUMAN ROR1_HUMAN NTRK1_HUMAN MUSK_HUMAN NTRK2_HUMAN NTRK3_HUMAN BTK_HUMAN TEC_HUMAN ITK_HUMAN TXK_HUMAN BMX_HUMAN FAK1_HUMAN FAK2_HUMAN EGFR_HUMAN ERBB3_HUMAN ERBB4_HUMAN ERBB2_HUMAN
Description protein tyrosine kinase ATP binding / kinase/ protein kinase/ protein serine/threonine kinase protein kinase family protein, putative, expressed N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. CG1511 Eph receptor tyrosine kinase CG10079 Epidermal growth factor receptor precursor (Egfr) (Gurken receptor) CG7873 Tyrosine-protein kinase Src42A (Dsrc41) CG7524 Tyrosine-protein kinase Src64B (Dsrc64) CG4032 Tyrosine-protein kinase Abl (Abelson protein) (D-ash) CG8874 Tyrosine-protein kinase Fps85D (dFer) CG4007 Tyrosine-protein kinase transmembrane receptor Ror2 precursor CG4926 Tyrosine-protein kinase transmembrane receptor Ror precursor CG8049 Tyrosine-protein kinase Btk29A (Dsrc28C) CG10023 Focal Adhesion Kinase Ephrin type-B receptor 1 precursor (Tyrosine-protein kinase receptor EPH-2) Ephrin type-B receptor 2 precursor (Tyrosine-protein kinase receptor EPH-3) Ephrin type-B receptor 3 precursor (Tyrosine-protein kinase receptor HEK-2) Ephrin type-B receptor 4 precursor (Tyrosine-protein kinase receptor HTK) Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) Ephrin type-A receptor 1 precursor (Tyrosine-protein kinase receptor EPH) Ephrin type-A receptor 2 precursor (Tyrosine-protein kinase receptor ECK) Ephrin type-A receptor 3 precursor (Tyrosine-protein kinase receptor ETK1) Ephrin type-A receptor 4 precursor (Tyrosine-protein kinase receptor SEK) Ephrin type-A receptor 5 precursor (Tyrosine-protein kinase receptor EHK-1) Ephrin type-A receptor 7 precursor (Tyrosine-protein kinase receptor EHK-3) Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) Ephrin type-A receptor 10 precursor Proto-oncogene tyrosine-protein kinase Src (p60-Src) Tyrosine-protein kinase FRK Proto-oncogene tyrosine-protein kinase Fyn (p59-Fyn) Proto-oncogene tyrosine-protein kinase Yes (p61-Yes) Proto-oncogene tyrosine-protein kinase FGR (P55-FGR) Tyrosine-protein kinase HCK (p59-HCK/p60-HCK) Proto-oncogene tyrosine-protein kinase LCK (p56-LCK) Tyrosine-protein kinase Lyn Tyrosine-protein kinase BLK (B lymphocyte kinase) (p55-BLK) Tyrosine-protein kinase Srms Proto-oncogene tyrosine-protein kinase ABL1 (p150) Tyrosine-protein kinase ABL2 (Abelson murine leukemia viral oncogene homolog 2) Proto-oncogene tyrosine-protein kinase Fes/Fps Proto-oncogene tyrosine-protein kinase FER (p94-FER) Tyrosine-protein kinase transmembrane receptor ROR2 precursor Tyrosine-protein kinase transmembrane receptor ROR1 precursor High affinity nerve growth factor receptor precursor Muscle, skeletal receptor tyrosine protein kinase precursor BDNF/NT-3 growth factors receptor precursor NT-3 growth factor receptor precursor Tyrosine-protein kinase BTK (Bruton tyrosine kinase) Tyrosine-protein kinase Tec Tyrosine-protein kinase ITK/TSK (T-cell-specific kinase) Tyrosine-protein kinase TXK Cytoplasmic tyrosine-protein kinase BMX Focal adhesion kinase 1 (FADK 1) (pp125FAK) Protein tyrosine kinase 2 beta (Focal adhesion kinase 2) Epidermal growth factor receptor precursor (Receptor tyrosine-protein kinase ErbB-1) Receptor tyrosine-protein kinase erbB-3 precursor (c-erbB3) Receptor tyrosine-protein kinase erbB-4 precursor (p180erbB4) Receptor tyrosine-protein kinase erbB-2 precursor (p185erbB2)
Table S1.17. Ephrin Receptor and ErbB Receptor families. Abbrevietion gi At TyrK 397645 Os TyrK 18408889 Dicty TyrK 108862829 Sponge Eph-like N.A. Sponge Src-like(1) N.A. Sponge Src-like(2) N.A. Sponge Abl-like N.A. Sponge Fps-like N.A. Sponge Ror-like N.A. Sponge FAK-like N.A. Sponge ErbB-like N.A. Fly Eph 62484409 Fly ErbB 6175066 Fly Src42 33112450 Fly Src64 14286176 Fly Abl 62512130 Fly Fps 44888970 Fly Ror2 27923847 Fly Ror1 27923846 Fly Btk 25453425 Fly FAK 24655701 Human Eph B1 1706663 Human Eph B2 76803654 Human Eph B3 76803655 Human Eph B4 19860819 Human Eph B6 6919882 Human Eph A1 47117832 Human Eph A2 125333 Human Eph A3 125387 Human Eph A4 1711371 Human Eph A5 1706628 Human Eph A7 68846922 Human Eph A8 19857975 Human Eph A10 74762207 Human Src 125711 Human FRK 1169745 Human Fyn 125370 Human Yes 125870 Human FGR 125358 Human HCK 20141296 Human LCK 125474 Human Lyn 125480 Human BLK 1705485 Human Srms 27805732 Human ABL1 85681908 Human ABL2 1168268 Human Fes 400127 Human FER 97536202 Human Ror2 90110767 Human Ror1 19924290 Human NTRK1 94730402 Human MUSK 50400806 Human NTRK2 2497560 Human NTRK3 2497562 Human BTK 547759 Human Tec 1174630 Human ITK 585361 Human TXK 1351326 Human BMX 1705489 Human FAK1 3183518 Human FAK2 3183003 Human ErbB1 2811086 Human ErbB3 119534 Human ErbB4 3913590 Human ErbB2 119533
Table S1.18. Neuroligin family. Abbrevietion Dicty CES-like Sponge CES-like CN NRL-like(1) CN NRL-like(2) CN NRL-like(3) CN NRL-like(4) CN NRL-like(5) CN NRL-like(6) Fly Neuroligin 1 Fly Neuroligin 2 Fly Gliotactin Fly ACES Human Neuroligin 3 Human Neuroligin 4X Human Neuroligin 4Y Human Neuroligin 1 Human Neuroligin 2 Human ACES Human CHLE Human CEL Human EST2 Human EST1
gi 66802562 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 7716610 28381150 24584488 113036 31076855 31076821 31076823 31076822 31076824 113037 116353 231629 46576349 119576
Table S1.19. Ionotropic Glutamate Receptor families. Abbrevietion gi At GLR33 39545692 Os GLR 50904793 CN NMDAR-like (1) N.A. CN NMDAR-like (2) N.A. CN NMDAR-like (3) N.A. CN NMDAR-like (4) N.A. CN NMDAR-like (5) N.A. CN NMDAR-like (6) N.A. CN NMDAR-like (7) N.A. CN NMDAR-like (8) N.A. CN GLR-like (1) N.A. CN GLR-like (2) N.A. CN GLR-like (3) N.A. Fly GLR 1 68067727 Fly GLR 2 24648559 Fly GLR 3 61699735 Fly GLR 4 23171826 Fly GLR 5 6687415 Fly GLR 6 24581972 Fly GLR 7 24648476 Fly GLR 8 24661440 Fly GLR 9 45549153 Fly GLR 10 22945551 Fly GLR 11 24581733 Fly GLR 12 116007354 Fly GLR 13 85682857 Fly GLR 14 24666122 Fly GLR 15 24666536 Fly GLR 16 24667182 Fly GLR 17 28572148 Fly GLR 18 85683065 Fly GLR 19 24644826 Fly NMDAR 1 24644257 Fly NMDAR 2 48095783 Human AMPAR 1 1169959 Human AMPAR 2 23831146 Human AMPAR 3 77416864 Human AMPAR 4 1346142 Human KainateR 1 729597 Human KainateR 2 2492627 Human KainateR 3 3287976 Human KainateR 4 3287848 Human KainateR 5 3287849 Human DeltaR 1 38372397 Human DeltaR 2 25090493 Human NMDAR 1 2343289 Human NMDAR 2A 14285603 Human NMDAR 2B 14548162 Human NMDAR 2C 2492629 Human NMDAR 2D 18201966 Human NMDAR 3A 51701684 Human NMDAR 3B 71153527
Swissprot Locus N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. ACES_DROME NLGN3_HUMAN NLGNX_HUMAN NLGNY_HUMAN NLGN1_HUMAN NLGN2_HUMAN ACES_HUMAN CHLE_HUMAN CEL_HUMAN EST2_HUMAN EST1_HUMAN
Description hypothetical protein DDBDRAFT_0183832 N.A. N.A. N.A. N.A. N.A. N.A. N.A. CG13772 neuroligin CG31146 CG3903 Gliotactin Acetylcholinesterase precursor (AChE) Neuroligin-3 precursor (Gliotactin homolog) Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX) Neuroligin-4, Y-linked precursor (Neuroligin Y) Neuroligin-1 precursor Neuroligin-2 precursor Acetylcholinesterase precursor (AChE) Cholinesterase precursor (Acylcholine acylhydrolase) Bile salt-activated lipase precursor (BAL) (Bile salt-stimulated lipase) (BSSL) Carboxylesterase 2 precursor (CE-2) (hCE-2) Liver carboxylesterase 1 precursor
Swissprot Locus N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. GLK1_DROME N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. GRIA1_HUMAN GRIA2_HUMAN GRIA3_HUMAN GRIA4_HUMAN GRIK1_HUMAN GRIK2_HUMAN GRIK3_HUMAN GRIK4_HUMAN GRIK5_HUMAN GRID1_HUMAN GRID2_HUMAN N.A. NMDE1_HUMAN NMDE2_HUMAN NMDE3_HUMAN NMDE4_HUMAN NMD3A_HUMAN NMD3B_HUMAN
Description GLR3.3 putative glutamate receptor N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. CG8442 Glutamate receptor 1 (dGLUR-I) CG3822 CG11155 CG5621 CG18039 KaiRIA ionotropic glutamate receptor subunit IA CG6992 Glutamate receptor IIA CG31201 Glutamate receptor IIE CG4481 Glutamate receptor IB CG7234 Glutamate receptor IIB CG4226 CG15627 CG8681 clumsy CG10633 CG14586 CG14076 CG7385 CG17274 CG32704 CG10101 CG2902 NMDA receptor 1 CG33513 NMDA receptor subunit 2 Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (AMPA 1) Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (AMPA 2) Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (AMPA 3) Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (AMPA 4) Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) Glutamate receptor delta-1 subunit precursor (GluR delta-1) Glutamate receptor delta-2 subunit precursor (GluR delta-2) NMDAR1 subunit Glutamate [NMDA] receptor subunit epsilon 1 precursor (NR2A) Glutamate [NMDA] receptor subunit epsilon 2 precursor (NR2B) Glutamate [NMDA] receptor subunit epsilon 3 precursor (NR2C) Glutamate [NMDA] receptor subunit epsilon 4 precursor (NR2D) Glutamate [NMDA] receptor subunit 3A precursor ( NR3A) Glutamate [NMDA] receptor subunit 3B precursor (NR3B)
Table S1.20. K+ Channel Kir family. Abbrevietion Sponge Kir-like 1 Sponge Kir-like 2 Fly Kir 1 Fly Kir 2 Fly Kir 3 Human Kir 1.3 Human Kir 1.2 Human Kir 1.1 Human Kir 7.1 Human Kir 2.2 Human Kir 2.3 Human Kir 2.1
gi N.A. N.A. 24649234 24649329 62484243 77416869 2493605 1352479 13878543 77416868 1352483 54037433
Swissprot Locus N.A. N.A. N.A. N.A. N.A. IRK15_HUMAN IRK10_HUMAN IRK1_HUMAN IRK13_HUMAN IRK12_HUMAN IRK4_HUMAN IRK2_HUMAN
Description N.A. N.A. CG6747 Inwardly rectifying potassium channel CG4370 Inwardly rectifying potassium channel 2 CG10369 Inwardly rectifying potassium channel 3 Inward rectifier K(+) channel Kir4.2 (Kir1.3) Inward rectifier K(+) channel Kir1.2 ATP-regulated potassium channel ROM-K (Kir1.1) Inward rectifier K(+) channel Kir7.1 Inward rectifier K(+) channel Kir2.2 Inward rectifier K(+) channel Kir2.3 Inward rectifier K(+) channel Kir2.1
Human Kir 2.4 Human Kir 5.1 Human Kir 3.2 Human Kir 3.4 Human Kir 3.3 Human Kir 3.1 Human Kir 6.1 Human Kir 6.2
54036159 13878562 1352487 1352484 2493603 1352482 2493600 76803775
IRK14_HUMAN IRK16_HUMAN IRK6_HUMAN IRK5_HUMAN IRK9_HUMAN IRK3_HUMAN IRK8_HUMAN IRK11_HUMAN
Inward rectifier K(+) channel Kir2.4 Inward rectifier K(+) channel Kir5.1 Inward rectifier K(+) channel Kir3.2 Inward rectifier K(+) channel Kir3.4 Inward rectifier K(+) channel Kir3.3 Inward rectifier K(+) channel Kir3.1 Inwardly rectifier K(+) channel Kir6.1 Inwardly rectifier K(+) channel Kir6.2
Table S1.21. K+ Channel Shaker family. Abbrevietion CN Kv 1-like(1) CN Kv 1-like(2) CN Kv 1-like(3) CN Kv 3-like Fly Kv 1 Fly Kv 3.1 Fly Kv 3.2 Human Kv 1.1 Human Kv 1.2 Human Kv 1.3 Human Kv 1.4 Human Kv 1.5 Human Kv 1.6 Human Kv 1.7 Human Kv 3.1 Human Kv 3.2 Human Kv 3.3 Human Kv 3.4
gi N.A. N.A. N.A. N.A. 13432103 28574020 45445057 1168947 1345813 1168948 116430 1705863 116434 14485555 1352085 21999191 8488974 66774206
Swissprot Locus N.A. N.A. N.A. N.A. KCNAS_DROME N.A. N.A. KCNA1_HUMAN KCNA2_HUMAN KCNA3_HUMAN KCNA4_HUMAN KCNA5_HUMAN KCNA6_HUMAN N.A. KCNC1_HUMAN N.A. KCNC3_HUMAN KCNC4_HUMAN
Description N.A. N.A. N.A. N.A. CG12348 Potassium voltage-gated channel protein Shaker CG2822 Shaker cognate w CG4450 Voltage-gated potassium channel subunit Kv1.1 Voltage-gated potassium channel subunit Kv1.2 Voltage-gated potassium channel subunit Kv1.3 Voltage-gated potassium channel subunit Kv1.4 Voltage-gated potassium channel subunit Kv1.5 Voltage-gated potassium channel subunit Kv1.6 voltage-gated potassium channel KCNA7 Voltage-gated potassium channel subunit Kv3.1 potassium voltage-gated potassium channel subfamily C member 2 Voltage-gated potassium channel subunit Kv3.3 Voltage-gated potassium channel subunit Kv3.4
Table S1.22. Classical Cadherin family. Abbrevietion Sponge Classical Cadherin Fly Dachsous Fly N-Cadherin Fly N-Cadherin2 Fly DE-Cadherin Human Dachsous Human N-Cadherin Human R-Cadherin Human E-Cadherin Human P-Cadherin Human M-Cadherin Human OB-Cadherin Human K-Cadherin Human T2-Cadherin Human Cadherin 7 Human Cadherin 9 Human BR-Cadherin Human Cadherin 18 Human Cadherin 20 Human Cadherin 24 Human PB-Cadherin Human VE-Cadherin Human Cadherin 19
gi N.A. 25090185 13124002 27923751 13124007 20139065 1705541 81175161 399166 115427 1705553 1705548 1705545 13431364 17367151 13431362 1705551 3023435 17366842 38257450 24211543 13432109 13431344
Swissprot Locus N.A. DS_DROME CADN_DROME CADN2_DROME CADE_DROME PCD16_HUMAN CADH2_HUMAN CADH4_HUMAN CADH1_HUMAN CADH3_HUMAN CAD15_HUMAN CAD11_HUMAN CADH6_HUMAN CAD10_HUMAN CADH7_HUMAN CADH9_HUMAN CAD12_HUMAN CAD18_HUMAN CAD20_HUMAN CAD24_HUMAN CAD22_HUMAN CADH5_HUMAN CAD17_HUMAN
Description N.A. CG17941 Protein dachsous precursor (Adherin) CG7100 Neural-cadherin precursor (Cadherin-N protein) (DN-cadherin) CG7527 Putative neural-cadherin 2 precursor (Cadherin-N2 protein) (DN2-cadherin) CG3722 DE-cadherin precursor (Protein shotgun) Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1) Neural-cadherin precursor (N-cadherin) (Cadherin-2) (CDw325 antigen) Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD) Epithelial-cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) Cadherin-3 precursor (Placental-cadherin) (P-cadherin) Muscle-cadherin precursor (M-cadherin) (Cadherin-15) Cadherin-11 precursor (Osteoblast-cadherin) (OB-cadherin) (OSF-4) Cadherin-6 precursor (Kidney-cadherin) (K-cadherin) Cadherin-10 precursor (T2-cadherin) Cadherin-7 precursor Cadherin-9 precursor Cadherin-12 precursor (Brain-cadherin) (BR-cadherin) (N-cadherin 2) Cadherin-18 precursor (Cadherin-14) Cadherin-20 precursor Cadherin-24 precursor Cadherin-22 precursor (Pituitary and brain cadherin) (PB-cadherin) Cadherin-5 precursor (Vascular endothelial-cadherin) (VE-cadherin) Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin)
Table S1.23. DLG, Shank, GRIP, MAGI, LIN-7, LIMK, Mint, Tamalin, Erbin, NOS, PICK1 and CASK families. Abbrevietion gi Swissprot Locus Description At SP PDZ Sponge DLG PDZ1 (AA 144 - 223) N.A. N.A. N.A. Sponge DLG PDZ2 (AA 274 - 353) N.A. N.A. N.A. Sponge DLG PDZ3 (AA 397 - 470) N.A. N.A. N.A. Sponge Lin7 PDZ (AA 111 - 185) N.A. N.A. N.A. Sponge GRIP PDZ1 (AA 35 - 109) N.A. N.A. N.A. Sponge GRIP PDZ2 (AA 136 - 210) N.A. N.A. N.A. Sponge GRIP PDZ4 (AA 278 - 354) N.A. N.A. N.A. Sponge GRIP PDZ5 (AA 376 - 447) N.A. N.A. N.A.
Sponge GRIP PDZ6 (AA 475 - 549) Sponge GRIP PDZ7 (AA 836 - 907) Sponge Shank PDZ (AA 495 - 574) Sponge NOS PDZ (AA 16 - 88) Sponge PICK1 PDZ (AA 13 - 87) Sponge Magi PDZ1 (AA 34 -108) Sponge Magi PDZ2 (AA 424 - 500) Sponge Magi PDZ3 (AA 561 - 631) Sponge Magi PDZ4 (AA 678 - 754) Sponge Magi PDZ5 (AA 790 - 863) Sponge Magi PDZ6 (AA 951 - 1026) Sponge Mint PDZ1 (AA 364 - 442) Sponge Mint PDZ2 (AA 443 - 515) Sponge Tamalin PDZ (AA 126 - 202) CN Erbin-like PDZ (AA 966 - 1046) CN CASK PDZ (AA 625 - 721) Fly DLG PDZ1 (AA 224 - 303) Fly DLG PDZ2 (AA 338 - 421) Fly DLG PDZ3 (AA 514 - 587) Fly Shank PDZ (AA 688 - 773) Fly Lin7 PDZ (AA 101 - 175) Fly GRIP PDZ1 (AA 90 - 165) Fly GRIP PDZ2 (AA 191 - 276) Fly GRIP PDZ3 (AA 289 - 386) Fly GRIP PDZ4 (AA 475 - 543) Fly GRIP PDZ5 (AA 582 - 661) Fly GRIP PDZ6 (AA 842 - 916) Fly GRIP PDZ7 (AA 985 - 1058) Fly CASK PDZ (AA 504 - 576) Fly PICK1 PDZ (AA 33 - 105) Fly Magi PDZ2 (AA 454 - 535) Fly Magi PDZ3 (AA 609 - 679) Fly Magi PDZ4 (AA 936 - 1012) Fly Magi PDZ5 (AA 1040 - 1114) Fly Mint PDZ1 (AA 995 - 1073) Fly Mint PDZ2 (AA 1087 - 1153) Fly LIMK PDZ (AA 186 - 274) Fly Tamalin PDZ (AA 139 - 219) Human SAP97 PDZ1 (AA 232- 311) Human SAP97 PDZ2 (AA 327 - 406) Human SAP97 PDZ3 (AA 474 - 547) Human C110 PDZ1 (AA 106 - 185) Human C110 PDZ2 (AA 201 - 280) Human C110 PDZ3 (AA 429 - 502) Human SAP102 PDZ1 (AA 139 - 218) Human SAP102 PDZ2 (AA 234 - 313) Human SAP102 PDZ3 (AA 394 - 467) Human PSD95 PDZ1 (AA 73 - 152) Human PSD95 PDZ2 (AA 168 - 247) Human PSD95 PDZ3 (AA 321 - 394) Human GRIP1 PDZ1 (AA 62 - 136) Human GRIP1 PDZ2 (AA 160 - 238) Human GRIP1 PDZ3 (AA 261 - 336) Human GRIP1 PDZ4 (AA 481 - 561) Human GRIP1 PDZ5 (AA 582 - 658) Human GRIP1 PDZ6 (AA 681 - 755) Human GRIP1 PDZ7 (AA 1014 - 1086) Human GRIP2 PDZ1 (AA 57 - 131) Human GRIP2 PDZ2 (AA 156 - 234) Human GRIP2 PDZ3 (AA 257 - 332) Human GRIP2 PDZ4 (AA 465 - 545) Human GRIP2 PDZ5 (AA 566 - 641) Human GRIP2 PDZ6 (AA 664 - 738) Human GRIP2 PDZ7 (AA 951 - 1023) Human Shank1 PDZ (AA 672 - 761) Human Shank2 PDZ (AA 46 - 131) Human Lin7A PDZ (AA 116 - 190) Human Lin7B PDZ (AA 101 - 175) Human Lin7C PDZ (AA 101 - 175) Human Erbin PDZ (AA 1330 - 1410) Human Densin_180 PDZ (AA 1455 - 1535) Human PICK1 PDZ (AA 31 - 105) Human CASK PDZ (AA 499 - 571) Human Magi1 PDZ1 (AA 26 -105) Human Magi1 PDZ2 (AA 480 - 556) Human Magi1 PDZ3 (AA 651 - 753) Human Magi1 PDZ4 (AA 849 - 925) Human Magi1 PDZ5 (AA 1007 - 1094) Human Magi1 PDZ6 (AA 1160 - 1234) Human Magi2 PDZ1 (AA 26 - 101) Human Magi2 PDZ2 (AA 434 - 510)
N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 51704269 51704269 51704269 24653538 21356237 24640023 24640023 24640023 24640023 24640023 24640023 24640023 34223738 28574146 20304109 20304109 20304109 20304109 24642814 24642814 74865306 45550544 2497504 2497504 2497504 73920200 73920200 73920200 2497506 2497506 2497506 71658825 71658825 71658825 48474711 48474711 48474711 48474711 48474711 48474711 48474711 48474948 48474948 48474948 48474948 48474948 48474948 48474948 22001988 22001987 59798442 59798472 59798474 50401131 50401129 22095990 27735175 52782748 52782748 52782748 52782748 52782748 52782748 88909269 88909269
N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. DLG1_DROME DLG1_DROME DLG1_DROME N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. CAKI_DROME N.A. N.A. N.A. N.A. N.A. N.A. N.A. LIMK1_DROME N.A. DLG1_HUMAN DLG1_HUMAN DLG1_HUMAN DLG2_HUMAN DLG2_HUMAN DLG2_HUMAN DLG3_HUMAN DLG3_HUMAN DLG3_HUMAN DLG4_HUMAN DLG4_HUMAN DLG4_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP1_HUMAN GRIP2_HUMAN GRIP2_HUMAN GRIP2_HUMAN GRIP2_HUMAN GRIP2_HUMAN GRIP2_HUMAN GRIP2_HUMAN SHAN1_HUMAN SHAN2_HUMAN LIN7A_HUMAN LIN7B_HUMAN LIN7C_HUMAN LAP2_HUMAN LRRC7_HUMAN PICK1_HUMAN CSKP_HUMAN MAGI1_HUMAN MAGI1_HUMAN MAGI1_HUMAN MAGI1_HUMAN MAGI1_HUMAN MAGI1_HUMAN MAGI2_HUMAN MAGI2_HUMAN
N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. CG1725 Discs large 1 tumor suppressor protein CG1725 Discs large 1 tumor suppressor protein CG1725 Discs large 1 tumor suppressor protein CG30483 Prosap CG7662 veli CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG14447 Glutamate receptor binding protein CG6703 Calcium/calmodulin-dependent protein kinase (CaMGUK) CG6167 PICK1 CG30388 Magi CG30388 Magi CG30388 Magi CG30388 Magi CG5675 X11L CG5675 X11L CG1848 LIM domain kinase 1 (LIMK-1) (dLIMK) CG6619 Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg) Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg) Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg) Discs large homolog 2 (Channel-associated protein of synapse-110) Discs large homolog 2 (Channel-associated protein of synapse-110) Discs large homolog 2 (Channel-associated protein of synapse-110) Discs large homolog 3 (Synapse-associated protein 102) (SAP102) Discs large homolog 3 (Synapse-associated protein 102) (SAP102) Discs large homolog 3 (Synapse-associated protein 102) (SAP102) Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 1 (GRIP1 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) Glutamate receptor-interacting protein 2 (GRIP2 protein) SH3 and multiple ankyrin repeat domains protein 1 (Shank1) SH3 and multiple ankyrin repeat domains protein 2 (Shank2) LIN-7 homolog A (LIN-7A) (hLin-7) (Mammalian LIN-seven protein 1) LIN-7 homolog B (LIN-7B) (hLin7B) (Mammalian LIN-seven protein 2) (MALS-2) LIN-7 homolog C (LIN-7C) (Mammalian LIN-seven protein 3) (MALS-3) LAP2 protein (Erbb2-interacting protein) (Erbin) (Densin-180-like protein) Leucine-rich repeat-containing protein 7 (LAP1 protein) (Densin-180) PRKCA-binding protein (Protein interacting with C kinase 1) Peripheral plasma membrane protein CASK (hCASK) Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Human Magi2 PDZ3 (AA 613 - 683) Human Magi2 PDZ4 (AA 786 - 862) Human Magi2 PDZ5 (AA 929 - 1010) Human Magi2 PDZ6 (AA 1155 - 1229) Human Magi3 PDZ1 (AA 27 - 106) Human Magi3 PDZ2 (AA 443 - 519) Human Magi3 PDZ3 (AA 611 - 681) Human Magi3 PDZ4 (AA 759 - 835) Human Magi3 PDZ5 (AA 885 - 963) Human Magi3 PDZ6 (AA 1054 - 1128) Human Mint1 PDZ1 (AA 665 - 743) Human Mint1 PDZ2 (AA 757 - 823) Human Mint2 PDZ1 (AA 577 - 655) Human Mint2 PDZ2 (AA 669 - 735) Human Mint3 PDZ1 (AA 403 - 481) Human Mint3 PDZ2 (AA 495 - 561) Human nNOS PDZ (AA 26 - 100) Human LIMK1 PDZ (AA 176 - 258) Human LIMK2 PDZ (AA 161 - 239) Human Tamalin 1 PDZ (AA 110 - 190)
88909269 88909269 88909269 88909269 27544925 27544925 27544925 27544925 27544925 27544925 6226838 6226838 6226950 6226950 6226953 6226953 1709333 90185240 1708824 74738818
MAGI2_HUMAN MAGI2_HUMAN MAGI2_HUMAN MAGI2_HUMAN N.A. N.A. N.A. N.A. N.A. N.A. APBA1_HUMAN APBA1_HUMAN APBA2_HUMAN APBA2_HUMAN APBA3_HUMAN APBA3_HUMAN NOS1_HUMAN LIMK1_HUMAN LIMK2_HUMAN GRASP_HUMAN
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 membrane-associated guanylate kinase-related 3 isoform 1 membrane-associated guanylate kinase-related 3 isoform 1 membrane-associated guanylate kinase-related 3 isoform 1 membrane-associated guanylate kinase-related 3 isoform 1 membrane-associated guanylate kinase-related 3 isoform 1 membrane-associated guanylate kinase-related 3 isoform 1 Amyloid beta A4 precursor protein-binding family A member 1 (Mint-1) Amyloid beta A4 precursor protein-binding family A member 1 (Mint-1) Amyloid beta A4 precursor protein-binding family A member 2 (Mint-2) Amyloid beta A4 precursor protein-binding family A member 2 (Mint-2) Amyloid beta A4 precursor protein-binding family A member 3 (Mint-3) Amyloid beta A4 precursor protein-binding family A member 3 (Mint-3) Nitric-oxide synthase, brain (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) LIM domain kinase 1 (LIMK-1) LIM domain kinase 2 (LIMK-2) Tamalin - General receptor for phosphoinositides 1-associated scaffold protein
