decreased unstressed volume, decreased compliance and volume infusion on mean circulatory filling pressure. The normal state is shown by the curve to the ...
c2,"25$%" H3/" ?"& X`G Q3/6/"M4"^ #62,/64 H3/&$3# M$44$2C +/"55:/"5 3/" 5"25"& .; 46VE+/"55:/" 5,/",#AE 6/ -"#A326/"#"+,6/5 3#/655 ,A" V344 6M ,A" /$CA, 3,/$:- 32& ,A" +:4-623/; 3/,"/;G = /"&:#,$62 $2 #3/&$3#
.466& %64:-" &"#/"35"5 ,A" M$/$2C /3," 6M 3MM"/"2, %3C34 M$."/5 ,6 ,A" #"2,/34 2"/%6:5 5;5,"- VA"/" ,A"; 5:5,3$2 3 ,62$# $2A$.$,$62 6M 5;-+3,A",$# 6:,M46V ,6 ,A" %35#:43E ,:/" _]J 0`G KA:5J VA"2 %"26:5 /",:/2 &"#/"35"5J /"&:#"& 3,/$34 5,/",#A 32& 46V"/ ,/325-:/34 +/"55:/"5 &$5$2A$.$, 5;-+3,A",$# 3#,$%$,; 32& ,A$5 $2#/"35"5 3/,"/$34 %356-6E ,6/ 32& %"26-6,6/ ,62" _(8J ((J (
5""- ,6 $-+3$/ -;6#3/&$34 #62,/3#,$4$,; &$/"#,4; %$3 3 2$E ,/$# 6^$&" 5;2,A35"E&"+"2&"2, -"#A32$5- _WWJ W>J W]J W0J >8`G h2 ,A" 3/,"/$34 5$&"J $2#/"35"& +/6&:#,$62 6M 2$E ,/$# 6^$&" $5 /"5+625$.4" M6/ -355$%" +"/$+A"/34 %356&$43E ,3,$62J &"+/"55"& %35#:43/ /"3#,$%$,; $2 /"5+625" ,6 "2E &6C"26:5 32& "^6C"26:5 %356#625,/$#,6/5J 32& $-E +3$/"& ,$55:" +"/M:5$62 _>(J >7J >BJ >)`G c2 #62,/35,J &:/$2C 5"+5$5 32& "2&6,6^"-$3 ,A"/" $5 $2#/"35"& /"5$5E ,32#" 32& A;+"/,"25$62 $2 %35#:43/ ."&5 V$,A %"26:5 #A3/3#,"/$5,$#5J $2#4:&$2C ,A" +:4-623/; #$/#:43,$62 _>W`G S2&6,6^"-$3 $2#/"35"5 +6/,34 %"26:5 +/"55:/" 32& ,A" %"26:5 +/"55:/"EM46V /"43,$625A$+ 6M ,A" 5+432#A2$# #$/#:43,$62 $5 5A$M,"& :+V3/&5J $G"G ,A"/" $5 &"#/"35"& %"E 26:5 .466& M46V M6/ 3 C$%"2 +6/,34 %"26:5 +/"55:/" _>>J >]`G KA$5 $-+3$/-"2, 6M +6/,34 .466& M46V 3++"3/5 ,6 ." #3:5"& .; 3#,$%" +6/,34E5$2:56$&34 #625,/$#,$62 32& .; %35#:43/ 6.5,/:#,$62 5"#62&3/; ,6 #"44 5V"44$2CJ A"-6/E /A3C" 32& #62C"5,$62 V$,A$2 ,A" 4$%"/ _>WJ >]`G KA"5" 34E ,"/3,$625 #62,/$.:," ,6 ,A" $2#/"35"& %"26:5 /"5$5,32#" 32& C"2"/3," 3 .3#PE+/"55:/" ,6 +6/,34 %"26:5 M46VG c2 3&&$,$62J 5"+5$5 32& "2&6,6^"-$3 -3; &$5/:+, ,A" 56E #344"& %"26E3/,"/$34 /"5+625" $2 ,A" 5+432#A2$# %35#:43/ ."&J 3 +A;5$646C$#34 -"#A32$5- ,A3, $2#/"35"5 -"5"2E ,"/$# 3/,"/$34 /"5$5,32#" 32& 4$-$,5 5+432#A2$# 3/,"/$34 .466& M46V VA"2 +6/,34 %"26:5 +/"55:/" $2#/"35"5 _>0J ]8`G KA:5J 3, ,A" 53-" ,$-" 35 %"26:5 6:,M46V M/6- ,A" 5+432#A2$# %35#:43/ ."& $5 $-+"&"& -"5"2,"/$# 3/,"/$34 %356&$43,3,$62 -3; 3:C-"2, .466& M46V ,6 ,A$5 /"C$62G c2 3556#$3,$62 V$,A $2#/"35"& %35#:43/ +"/-"3.$4$,;J ,A$5 #3:5"5 5+432#A2$# .466& +664$2C 32& "&"-3 M6/-3,$62 _](`G KA"5" M3#,6/5 #62,/$.:," ,6 ,A" 4655 6M #$/#:43,$2C .466& %64:-" 32& &"#/"35"& #3/&$3# +/"463& #:4-$23,E $2C $2 5"+,$# 5A6#PG I$CA +"/$+A"/34 .466& M46V &"-32&5 c2 3&:4, A:-325 ,A" -3^$-34 #3/&$3# 6:,+:, $5 3.6:, J 0]`G I6V"%"/J 5:.5,32,$34 "%$&"2#" 5:CC"5,5 ,A3, !E3&/"2"/C$# /"#"+,6/5 -3; 3456 ." $2%64%"& $2 ,A" #62,/64 6M %"26:5 #3+3#$,32#"G 16/ "^3-+4"J "+$2"+AE /$2" $2#/"35"5 #3/&$3# M$44$2C +/"55:/"5 $2 &6C5 VA"2 #3/E &$3# 6:,+:, $5 A"4& #625,32, .; %"2,/$#:43/ +3#$2Cj ,A$5 /"5+625" $5 -3/P"&4; 3,,"2:3,"& &:/$2C !E/"#"+,6/ .46#P3&" V$,A +/6+/326464 _(0`G *$2#" !E3C62$5,5J "GCG $56+/6,"/"264J A3%" -$2$-34 "MM"#,5 62 ,A" -"32 #$/#:43E ,6/; M$44$2C +/"55:/" _` 32& 32 $2#/"35" 6M M/3#,$6234 .466& M46V ,6 /"C$625 V$,A M35, ,$-" #625,32,5 _)7J )BJ 00`G c2 5:--3/;J ,A/6:CA ,A"$/ "MM"#,5 62 ,A" +"/$+A"/34 #$/#:43,$62J #3,"#A643-$2"5 -3; ." "MM"#,$%" $2 $2#/"35E $2C %"26:5 /",:/2G I6V"%"/J ."M6/" "^6C"26:5 5;-+3E ,A",$# 5,$-:43,$62 $5 +/6%$&"& ,6 3 #/$,$#344; $44 +3,$"2, VA65" "2&6C"26:5 %356#625,/$#,6/ ,62" -3; 34/"3&; ." "^,/"-"J ,A" $2,/3%35#:43/ %64:-" 5,3,:5 5A6:4& ." 6+,$-$d"&G =456 ."3/ $2 -$2& ,A3, $2,"25" 3/,"/$34 %356E #625,/$#,$62J VA$4" /"5,6/$2C /"5$5,32#" 32& .466& +/"5E 5:/"J -3; ." 3556#$3,"& V$,A 3 5$C2$M$#32, /"&:#,$62 $2 .466& M46VG 16/ "^3-+4"J $2 5"+5$5J 26/"+$2"+A/$2" -3; /"&:#" 5+432#A2$# .466& +664$2C .; $2#/"35$2C -"5"2E ,"/$# /"5$5,32#"J .:, ,A" #62#6-$,32, /"&:#,$62 $2 5+432#A2$# M46V -3; 3CC/3%3," 56-" +/"E"^$5,$2C $5E #A"-$3 $2 ,A" C:, 32& 4$%"/ _(88`G c2A$.$,$62 6M 2$,/$# 6^$&" 5;2,A35" XUh*Y A35 .""2 $2%"5,$C3,"& 35 3 M:/,A"/ 3++/63#A $2 -6&$M;$2C %35#:43/ ,62"G c2 #62&$,$625 6M #4$2$#34 32& "^+"/$-"2,34 5"+5$5J Uh* $2A$.$,6/5 3/" "MM"#,$%" $2 /"%"/5$2C 5;5,"-$# A;E +6,"25$62 _0)J (8(J (88( 0G ?3/P =RJ ?32#$3 N X(0]7Y H3/&$6E +:4-623/; .3/6/"M4"^"5 $2 A:-325G c2' I32&.66P 6M @A;5$646C;G KA" #3/E &$6%35#:43/ 5;5,"-' #$/#:43,$62G =@A;5$64 *6#J Q",A"5&3J ?&G *"#, )f)]) >Y ?"#A32$5- 6M 3#,$62 6M $56+/6,"/"264 62 %"26:5 /",:/2G =- 9 @A;5$64 f(B) 70Y !"M4"^ #3/&$6%35#:43/ &"+/"55$62 &:/$2C :2$43,"/34 4:2C A;E +"/$2M43,$62 $2 ,A" &6CG 9 H4$2 c2%"5, WB' WY SMM"#,5 6M +65$,$%" "2&E"^E +$/3,6/; +/"55:/" 62 A"+3,$# .466& M46V 32& +"/M6/-32#"G 9 =++4 @A;5$64 WBY SMM"#, 6M "+$2"+A/$2" 62 +/"55:/"J M46V 32& %64:-" /"43,$62E 5A$+5 $2 ,A" 5;5,"-$# #$/#:43,$62 6M &6C5G H$/# !"5 7B' W8WfW
)BG ?$,d2"/ OJ N64&."/C I X(0>)Y SMM"#,5 6M "+$2"+A/$2" 62 /"5$5,$%" 32& #6-E +4$32, +/6+"/,$"5 6M ,A" #32$2" %35#:43E ,:/"G 9 =++4 @A;5$64 70' f7)W )]G R:2&%344 9J Ru22" K X(0]0Y R3/C" #3E +3#$,; $2 -32 M6/ "MM"#,$%" +435-3 %64E :-" #62,/64 $2 A;+6%64"-$3 %$3 M4:$& ,/325M"/ M/6- ,$55:" ,6 .466&G =#,3 @A;5$64 *#32& (7>' )(7f)]Y 14:$& ,/325M"/ M/6- 5P"4",34 -:5#4" ,6 .466& &:/$2C A"-6//A3C"G c-+6/,32#" 6M .",3E3&/"2"/C$# %35#:43/ -"#A32$5-5G =#,3 @A;5$64 *#32& (8(G @$25P; ?!J ?3,:5#A3P N? X(0]WY H3/&$6%35#:43/ &","/-$232,5 6M ,A" A"-6&;23-$# /"5+625" ,6 3#:," "2E &6,6^"-$3 $2 ,A" &6CG 9 H/$, H3/" (' (]f7( >]Wf>0< >BG 1$4"+ 9J 164&"5E1$4"+ SJ !6:55"3: =J *$/6$5 @J 16:/2$"/ = X(007Y F35#:43/ /"5+625"5 ,6 "2&6,A"4$2E( M6446V$2C $2E A$.$,$62 6M 2$,/$# 6^$&" 5;2,A"5$5 $2 ,A" #625#$6:5 /3,G Q/ 9 @A3/-3#64 ((8' (G Q/$"2d3 UJ =;:5" KJ !"%"44; 9@J hpZ622"44 H@J !6.6,A3- 9R X(00)Y SMM"#,5 6M "2&6,6^$2 62 $5643,"& +6/E #$2" 4$%"/G @/"55:/"EM46V 3234;5$5G 9 =++4 @A;5$64 >]' >]Bf>0< >]G =;:5" KJ Q/$"2d3 UJ !"%"44; 9@J hpZ622"44 H@J Q6$,26,, 9mJ !6.6E ,A3- 9R X(00)Y =4,"/23,$625 $2 4$%"/ A"-6&;23-$#5 $2 32 $2,3#, +6/#$2" -6&"4 6M "2&6,6^$2 5A6#PG =- 9 @A;5E $64 8Wf>((
]8G !"%"44; 9@J =;:5" KJ Q/$"2d3 UJ !6.6E ,A3- 9R X(00)Y Z;5/"C:43,$62 6M ,A" %"26E3/,"/$34 /"5+625" $2 ,A" 5:+"/$6/ -"5"2,"/$# 3/,"/; &:/$2C "2&6,6^$# 5A6#PG H/$, H3/" ?"& (f(B>> ]
