The serum protein carbonyl content level in relation to ...

5 downloads 211748 Views 489KB Size Report
88.4±10.1. 84.2±11.1. P=0.07. Resting BP (mmHg). Systolic BP. 122.3±13.3 ... 2013, IP: 59.183.43.4] || Click here to download free Android application for this ...
[Downloaded free from http://www.ijhas.in on Wednesday, November 20, 2013, IP: 59.183.43.4]  ||  Click here to download free Android application for this journal

Short Communication

The serum protein carbonyl content level in relation to exercise stress test Titiporn Mekrungruangwong1,2, Porrnthanate Seenak1,2, Saowanee Luangaram1,3, Tomon Thongsri4, Sarawut Kumphune1,5 Department of Cardiao-Thoracic, Biomedical Research Unit in Cardiovascular Sciences (BRUCS) Faculty of Allied Health Sciences, Department of Cardiao-Thoracic Technology, Faculty of Allied Health Sciences, 3Department of Physical Therapy, Faculty of Allied Health Sciences, 4Department of Medicine, Buddhachinaraj Hospital, 5Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand 1 2

INTRODUCTION

ABSTRACT Background: Protein carbonyl (P) is oxidatively-modified protein with diagnostic potential for acute myocardial infarction. However, many findings indicated the elevation of serum PC content level related to exercise, which could cause false positive results and limiting the specificity for acute coronary syndrome diagnosis. This study aims to evaluate the level of serum protein carbonyl content in healthy volunteers subjected to exercise stress test (EST). Materials and Methods: Serum from healthy volunteers was collected 5-10 min before performing EST and 1 hour after the EST was achieved. The serum was collected, and the serum PC content level was determined by spectrophotometric DNPH assay. Results: The serum PC content level after exercise stress test was significantly higher than that of before performing EST (0.373 ± 0.05 nM/mg vs. 0.275 ± 0.02 nM/mg, P