Publis hed Quar ter ly Mangalor e, S outh I ndia I S S N 0972- 5997 Volume 3; I s s ue 3; July- S eptember 2004
Short Report
The Study Of Serum Prostate Specific Antigen And Phosphatase Isoenzymes Activity As Diagnostic Parameters In Patients With Prostate Cancer In Nigeria Igwe CU1, Ikaraoha CI1, Ogunlewe JO2, Nwobu GO1, Duru LAD2, Mokogwu ATH1 1Dept. of Medical Laboratory Sciences, Faculty of Pathological Sciences, College Of Medicine, Ambrose Alli University, Ekpoma 2Department of Chemical Pathology, Lagos State University Teaching Hospital, Lagos, Nigeria Address for Correspondence: Igwe, Chidi U. Department of Medical Laboratory Sciences, Faculty of Pathological Sciences, College of Medicine, Ambrose Alli University, P.M.B 14, Ekpoma, Edo State, Nigeria. E-mail:
[email protected] Citation: Igwe CU, Ikaraoha CI, Ogunlewe JO, Nwobu GO, Duru LAD, Mokogwu ATH. The Study Of Serum Prostate Specific Antigen And Phosphatase Isoenzymes Activity As Diagnostic Parameters In Patients With Prostate Cancer In Nigeria.Online J Health Allied Scs. 2004;3:3 URL: http://www.ojhas.org/issue11/2004-3-3.htm Open Access Archive: http://cogprints.ecs.soton.ac.uk/view/subjects/OJHAS.html Abstract: Serum activities of Acid Phosphatase (ACP) and Prostatic Acid Phosphatase (PAP) are still employed in most hospitals in Nigeria for the diagnosis of prostate cancer, because of lack of resources for prostate specific antigen (PSA) assay. Serum PSA and activities of phosphatase isoenzymes ACP and PAP, Alkaline Phosphatase (ALP) and Heat stable Alkaline Phosphatase (HSAP) were studied in 71 apparently healthy male controls and 47 proven prostate cancer patients. There were statistically significant increases in the mean serum levels of PSA, PAP, ACP, ALP and HSAP in the prostate cancer patients compared to the controls
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