Thyroid Disorders & Therapy
Chulam TC, Thyroid Disorders Ther 2014, 3:1 http://dx.doi.org/10.4172/2167-7948.1000146
Research Article
Open Access
Prognostic Factors in Patients with Well-Differentiated Thyroid Carcinoma with Locoregional Recurrence Submitted for Salvage Treatment Bernardo Fontel Pompeo1, ThiagoCelestino Chulam2, Ana Lucia Noronha Francisco2 andLuiz Paulo Kowalski2 1Surgery 2Head
Department – IBCC, Sao Paulo, Brazil
and Neck Surgery and Otorhinolaryngology Department, A C Camargo Hospital, Antonio Prudente Foundation, Sao Paulo, Brazil
*Corresponding
author:ThiagoCelestinoChulam, Surgeon Member of Head and Neck Surgery and Otorhinolaringology Department of A C Camargo Hospital. Professor Antonio Prudente Street, 211 Sao Paulo, Brazil-01509-900,Fax: 55-11-3277-6789; E-mail:
[email protected] Rec date: Nov 16, 2013,Acc date: Feb 25, 2014,Pub date: Feb 27, 2014 Copyright:© 2014 Chulam TC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract Background: Well-differentiated thyroid carcinoma is characterized by an excellent prognosis; however, recurrence rates range from 5% to 23%, and mortality after salvage treatment ranges from 38% to 69%. Objectives: To identify prognostic factors in patients who have undergone salvage therapy for well-differentiated thyroid carcinoma. Patients and methods: This is a retrospective cohort series including 102 patients with respectable locoregional recurrences who underwent salvage treatment. One hundred twenty loco-regional recurrences were observed amongst 102 patients. Univariate survival analysis was performed using the Kaplan-Meier method. Results: Five-year overall survival rates were significantly associated with age over 45 years (67.6%) (p
