outbreak of tuberculosis has happened, and another patient has become unwell.. This might be a case for the modmedmicro research group⦠We need to get ...
Issue 1 Volume 1
i’ll make sure we’ve got all
A
the information we need to
n
analyse this sample...
outbreak of tuberculosis We need to isolate this patient
has happened,
and start treatment. but
and another
Current technology will only
patient has
give us some answers...
become unwell..
Woo-hoo! DNA extraction done!- now we need to
This might be a Splutter
sequence it
Doctor Tim sends his lab samples to
case for the
COUGH
SPLUTTER
modmedmicro
research group…
have the DNA of the bacteria investigated.
The Doctors
The Research Nurses
The Research Assistants and scientists ….this sample shows tb...but it’s not
We need to get this just
right… the reliability of the
part of the wider outbreak—and it
data depends on us!
looks fully treatable
Reading dna
AT
CC
We’ve got it! Here’s the DNA sequence,
>SA
MPL
E 4 2 W S EQU ENC >QU E D ALI ATA TY SCO RES >RA
GT
CA
A !! HMMM…
and the variations in the genetic code….
associated with antibiotic resistance...
The Bioinformaticians
The Post-Docs
this sequence seems to be
The Population Geneticists
There’s no way this could
happen by chance… the p value
Servers working at 100%, data secure and safe...
is miniscule..
From our work we can learn how bacteria spread, how they become resistant to
TRANSFERRING and linking the data... It’s true. We can use this to
We should inform the wider
antibiotics, and
scientific community!
improve the care of patients with
predict whether treatment
Meanwhile in the IT department...
will work!
The Statisticians
infections
Together we are Modernising Medical Microbiology Oxford
Our team leaders:
Prof. Derrick Crook
Prof. sarah walker
Prof. tim Peto
you can find out more about the science that inspired this at http://twitter.com/ModMedMicro And www.medmedmicro.nsms.ox.ac.uk
