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Apr 28, 2015 - solifenacin intermediate with (1S)-1-phenyl-1,2,3,4-tetrahy- .... used at an amount of 2 mL to 20 mL per 1 g of (R)-quinucli- ... performed for 2 hours to 12 hours at the mentioned tempera- ... The organic acid may be formic acid, acetic ... tion obtained after the completion of the reaction of Reaction aliphatic ...